MEX3C

Gene Symbol	MEX3C
Entrez Gene	51320
Alt Symbol	BM-013, MEX-3C, RKHD2, RNF194
Species	Human
Gene Type	protein-coding
Description	mex-3 RNA binding family member C
Other Description	RING finger and KH domain-containing protein 2|RING finger protein 194|RNA-binding E3 ubiquitin-protein ligase MEX3C|RNA-binding protein MEX3C|ring finger and KH domain containing 2
Swissprots	Q9NZE3 A1L022 Q5U5Q3
Accessions	EAW62989 Q5U5Q3 AF208855 AAF64269 AK096190 BAG53227 AL833519 AW079942 AY950679 AAY34147 BC032952 BC041122 AAH41122 BC063244 BC146416 AAI46417 BC148855 AAI48856 BC153820 AAI53821 KC456343 AGI99528 KC456344 AGI99529 NM_016626 NP_057710
Function	E3 ubiquitin ligase responsible for the post- transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation. {ECO:0000269|PubMed:22863774, ECO:0000269|PubMed:23446422}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17267406}. Nucleus {ECO:0000269|PubMed:17267406}. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. May act as suppressor of replication stress and chromosome missegregation.
Tissue Specificity	Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus. Highly expressed in cells of the innate immune system, in particular activated NK cells. Week expression in the intestine. {ECO:0000269|PubMed:17267406, ECO:0000269|PubMed:22863774}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human MEX3C full length protein - ab162509 from Abcam Category Protein Source Wheat germ Species Human

MEX3C Antibody Blocking Peptide - LS-E30594 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MEX3C Antibody Blocking Peptide - LS-E27899 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MEX3C Protein - H00051320-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MEX3C Peptide - NBP1-76341PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Rkhd2 Peptide - GTX85374-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

MEX3C Peptide - AC21-2890-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MEX3C / RKHD2 - H00051320-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MEX3C / RKHD2 - H00051320-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MEX3C / RKHD2 Control Peptide - AP30732CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Rkhd2 Peptide - 4857P from ProSci Category Peptide Species Human

MEX3C fusion protein - Ag19028 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

MEX3C fusion protein - ag18931 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MEX3C, His-tagged - MEX3C-844H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human MEX3C - MEX3C-1030H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human RNA-binding protein MEX3C(MEX3C) - CSB-YP729263HU CSB-EP729263HU CSB-BP729263HU CSB-MP729263HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Mex3C Protein - abx163219 from Abbexa Category Protein Species Human

MEX3C, Peptide - MBS427984 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

MEX3C Protein - NBP1-81932PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MEX3C-Blocking-Peptide-C-term - BP20253b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MEX3C Peptide, Human - M34GP09449H from Creative Peptides Category Peptide Source Synthetic. Species Human

RNA-binding protein MEX3C (MEX3C), Recombinant Protein - MBS1296940 from MyBioSource Category Protein Prices $1,460.00, $1,460.00, $1,685.00, $1,685.00, $2,480.00, $2,480.00, $2,925.00, $2,925.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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