Gene Symbol | ASGR2 |
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Entrez Gene | 433 |
Alt Symbol | ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2 |
Species | Human |
Gene Type | protein-coding |
Description | asialoglycoprotein receptor 2 |
Other Description | C-type lectin domain family 4 member H2|HBxAg-binding protein|hepatic lectin H2 |
Swissprots | A8MT12 D3DTN0 D3DTM9 P07307 A6NLV8 Q03969 O00448 |
Accessions | EAW90259 EAW90260 EAW90261 EAW90262 EAW90263 EAW90264 P07307 AF529374 AAQ09608 AK303787 BAG64744 AK310123 BC017251 AAH17251 BM561839 BX483468 DC315727 DQ892652 ABM83578 DQ895891 ABM86817 M11025 AAB59519 U97197 AAB58308 X55283 CAA38997 X55284 XM_005256648 XP_005256705 XM_006721524 XP_006721587 XM_006721525 XP_006721588 XM_006721526 XP_006721589 XM_011523862 XP_011522164 XM_011523863 XP_011522165 XM_011523864 XP_011522166 XM_011523865 XP_011522167 XM_011523866 XP_011522168 NM_001181 NP_001172 NM_001201352 NP_001188281 NM_080912 NP_550434 NM_080913 NP_550435 NM_080914 NP_550436 |
Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
Top Pathways | Thyroid hormone synthesis |
ASGR2 Lysate(Denatured) - H00000433-T01 from Acris Antibodies
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ASGR2 overexpression lysate - LY408999 from Acris Antibodies
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ASGR2 overexpression lysate - LY409000 from Acris Antibodies
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ASGR2 overexpression lysate - LY409001 from Acris Antibodies
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ASGR2 overexpression lysate - LY420082 from Acris Antibodies
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ASGR2 overexpression lysate - LY429979 from Acris Antibodies
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ASGR2 293 Cell Lysate - 409405 from ABBIOTEC
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ASGR2 293 Cell Lysate - 404826 from ABBIOTEC
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ASGR2 293 Cell Lysate - 404827 from ABBIOTEC
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Asialoglycoprotein Receptor 2 Overexpression Lysate (Denatured) - H00000433-T01 from Novus Biologicals
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Asialoglycoprotein Receptor 2 Overexpression Lysate (Native) - NBL1-07763 from Novus Biologicals
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Asialoglycoprotein Receptor 2 Overexpression Lysate (Native) - NBP2-05750 from Novus Biologicals
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ASGR2 Over-expression Lysate Product - GWB-9F2460 from Genway Biotech
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ASGR2 Over-expression Lysate Product - GWB-8179CF from Genway Biotech
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ASGR2 Over-expression Lysate Product - GWB-3196F6 from Genway Biotech
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Human ASGR2 / ASGPR2 HEK293 Cell Lysate (WB positive control) - 13908-H07HL-300 from Sino Biological
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Human ASGR2 Human Cells Transfected Lysate (positive control) (denatured) - orb174187 from Biorbyt
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Asialoglycoprotein Receptor 2 Overexpression Lysate (Native) - NBL1-07764 from Novus Biologicals
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Asialoglycoprotein Receptor 2 Overexpression Lysate (Native) - NBP2-10961 from Novus Biologicals
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Panoply™ Human ASGR2 Knockdown Stable Cell Line - CSC-DC001038 from Creative biogene
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