Gene Symbol | ASGR2 |
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Entrez Gene | 433 |
Alt Symbol | ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2 |
Species | Human |
Gene Type | protein-coding |
Description | asialoglycoprotein receptor 2 |
Other Description | C-type lectin domain family 4 member H2|HBxAg-binding protein|hepatic lectin H2 |
Swissprots | A8MT12 D3DTN0 D3DTM9 P07307 A6NLV8 Q03969 O00448 |
Accessions | EAW90259 EAW90260 EAW90261 EAW90262 EAW90263 EAW90264 P07307 AF529374 AAQ09608 AK303787 BAG64744 AK310123 BC017251 AAH17251 BM561839 BX483468 DC315727 DQ892652 ABM83578 DQ895891 ABM86817 M11025 AAB59519 U97197 AAB58308 X55283 CAA38997 X55284 XM_005256648 XP_005256705 XM_006721524 XP_006721587 XM_006721525 XP_006721588 XM_006721526 XP_006721589 XM_011523862 XP_011522164 XM_011523863 XP_011522165 XM_011523864 XP_011522166 XM_011523865 XP_011522167 XM_011523866 XP_011522168 NM_001181 NP_001172 NM_001201352 NP_001188281 NM_080912 NP_550434 NM_080913 NP_550435 NM_080914 NP_550436 |
Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
Top Pathways | Thyroid hormone synthesis |
Human Asialoglycoprotein Receptor 2 full length protein - ab116745 from Abcam
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Human Asialoglycoprotein Receptor 2 protein fragment - ab134625 from Abcam
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ASGR2 Blocking Peptide - LS-E11964 from LifeSpan Bioscience
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Asialoglycoprotein Receptor 2 Recombinant Protein - H00000433-P01 from Novus Biologicals
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Recombinant Human Asialoglycoprotein Receptor 2 Protein - NBP2-22697 from Novus Biologicals
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Human ASGR2 protein - orb167932 from Biorbyt
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Human ASGR2 protein (His Tag) - orb138215 from Biorbyt
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ASGR2 Blocking Peptide - 33R-5548 from Fitzgerald
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ASGR2 Blocking Peptide - 33R-8876 from Fitzgerald
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ASGR2 protein (His tag) - 80R-2528 from Fitzgerald
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ASGR2 (80-311, His-tag) - AR50600PU-N from Acris Antibodies
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ASGR2 (80-311, His-tag) - AR50600PU-S from Acris Antibodies
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ASGR2 - H00000433-P01-10 from Acris Antibodies
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ASGR2 - H00000433-P01-25 from Acris Antibodies
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ASGR2, 80-311aa, Human, His tag, E.coli - 01-P1776 from ARP American Research Products
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ASGR2 fusion protein - Ag2037 from Proteintech Group
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ASGR2 Human - PRPS-1268 from NeoScientific
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ASGR2, 80-311aa, Recombinant Protein - GWB-P0262B from Genway Biotech
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Recombinant Human ASGR2 - ASGR2-26516TH from Creative Biomart
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Recombinant Human Asialoglycoprotein Receptor 2, His-tagged - ASGR2-7208H from Creative Biomart
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Recombinant Human ASGR2, His tagged - ASGR2-7375H from Creative Biomart
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Recombinant Human ASGR2, GST-tagged - ASGR2-9932H from Creative Biomart
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Recombinant Asialoglycoprotein Receptor 2 (ASGR2) - RPC067Hu01 from Uscn Life Science Inc.
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Human ASGR2 / ASGPR2 Protein (His Tag) - 13908-H07H-20 from Sino Biological
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Recombinant Asialoglycoprotein Receptor 2 (ASGR2) - RPC067Hu01 from Cloud-clone
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