CYP24A1

Gene Symbol CYP24A1
Entrez Gene 1591
Alt Symbol CP24, CYP24, HCAI, P450-CC24
Species Human
Gene Type protein-coding
Description cytochrome P450, family 24, subfamily A, polypeptide 1
Other Description 1,25-@dihydroxyvitamin D3 24-hydroxylase|1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial|24-OHase|cytochrome P450 24A1|cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)|cytochrome P450-CC24|exo-mitochondrial protein|vitamin D 24-hydroxylase|vitamin D(3) 24-hydroxylase
Swissprots Q15807 Q07973 Q5I2W7 Q32ML3
Accessions AAB03776 EAW75573 Q07973 AI400154 AW022349 AY858838 AAW50795 BC109083 AAI09084 BC109084 AAI09085 BI491491 BM928702 BU662901 CN311231 L13286 AAA62379 N29030 S67623 AAB29308 XM_005260304 XP_005260361 NM_000782 NP_000773 NM_001128915 NP_001122387
Function Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Subcellular Location Mitochondrion.
Top Pathways MicroRNAs in cancer, Steroid biosynthesis

CYP24 (E-7) - sc-365700 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP24 (E-7): sc-365700. Western blot analysis of CYP24 expression in MOLT-4 whole cell lysate.

CYP24 (G-15) - sc-32165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP24 (H-87) - sc-66851 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP24 (H-87): sc-66851. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells.

CYP24 (S-20) - sc-32164 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP24 (C-18) - sc-32166 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP24 (C-18): sc-32166. Western blot analysis of CYP24 expression in mouse pancreas (A) and mouse liver (B) tissue extracts.

Anti-CYP24A1 antibody - ab189322 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-CYP24A1 antibody (ab189322) at 0.1 µg/ml + Human liver lysate at 35 µgdeveloped using the ECL technique

Anti-CYP24A1 antibody - ab96691 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CYP24A1 antibody (ab96691) at 1/3000 dilutionLane 1 : 293T whole cell lysate Lane 2 : A431 whole cell lysate Lane 3 : H1299 whole cell lysate Lane 4 : HeLa S3 whole cell lysate Lane 5 : HepG2 whole cell lysate Lane 6 : MOLT4 whole cell lysate Lane 7 : Raji whole cell lysate Lysates/proteins at 30 µg per lane.

Anti-CYP24A1 antibody - ab109632 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-CYP24A1 antibody (ab109632) at 0.1 µg/ml + Human liver lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-CYP24A1 antibody - ab136106 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CYP24A1 antibody (ab136106) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-CYP24A1 antibody - ab54594 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab54594 CYP24A1 antibody at 1ug/ml.

Anti-CYP24A1 antibody [EPR9394] - ab137116 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9394
All lanes : Anti-CYP24A1 antibody [EPR9394] (ab137116) at 1/1000 dilutionLane 1 : Human fetal kidneyLane 2 : Human fetal liverLane 3 : Human placenta lysates Lysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilutiondeveloped using the ECL technique

Anti-CYP24A1 antibody - C-terminal - ab175976 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP24A1 antibody - C-terminal (ab175976) at 1/1000 dilution + Mouse spleen tissue lysate at 35 µg

Anti-CYP24 / CYP24A1 Antibody (aa411-460) - LS-C119489 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using Cytochrome P450 24A1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CYP24 / CYP24A1 Antibody (aa420-469) - LS-C135726 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP24A1 / CYP24 antibody LS-C135726 Western blot of Placenta lysate. Antibody concentration 1 ug/ml.

Anti-CYP24 / CYP24A1 Antibody (aa263-312) - LS-C135727 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP24A1 / CYP24 antibody LS-C135727 Western blot of MDA-MB-435S cell lysate.

Anti-CYP24 / CYP24A1 Antibody (aa390-439) - LS-C291854 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP24 / CYP24A1 Antibody (aa260-514, Biotin) - LS-C299535 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP24 / CYP24A1 Antibody (aa260-514, FITC) - LS-C303890 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP24 / CYP24A1 Antibody (aa260-514) - LS-C293634 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of recombinant CYP24 / CYP24A1.

Anti-CYP24 / CYP24A1 Antibody (Arg439) - LS-C176852 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of CYP24A1 (R439) pAb in paraffin-embedded human prostate carcinoma tissue.

Anti-CYP24 / CYP24A1 Antibody (aa241-514) - LS-C185746 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP24A1 antibody detects CYP24A1 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. CYP24A1 antibody dilution:1:500.

Anti-CYP24 / CYP24A1 Antibody (clone 1E1) - LS-C197015 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1E1
Western Blot analysis of CYP24A1 expression in transfected 293T cell line by CYP24A1 monoclonal antibody (M02), clone 1E1.Lane 1: CYP24A1 transfected lysate (Predicted MW: 11.11 KDa).Lane 2: Non-transfected lysate.

Anti-CYP24 / CYP24A1 Antibody (Internal) IHC-plus™ - LS-B9225 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Anti-CYP24 / CYP24A1 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CYP24 / CYP24A1 Antibody (aa473-502) - LS-C167212 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human spleen tissue reacted with CYP24A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

CYP24A1 Antibody (1E1.) - H00001591-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E1.
Western Blot: CYP24A1 Antibody (1E1) [H00001591-M02] - Analysis of CYP24A1 expression in transfected 293T cell line by CYP24A1 monoclonal antibody (M02), clone 1E1.Lane 1: CYP24A1 transfected lysate (Predicted MW: 11.11 KDa).Lane 2: Non-transfected lysate.
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