CYP24A1

Gene Symbol CYP24A1
Entrez Gene 1591
Alt Symbol CP24, CYP24, HCAI, P450-CC24
Species Human
Gene Type protein-coding
Description cytochrome P450, family 24, subfamily A, polypeptide 1
Other Description 1,25-@dihydroxyvitamin D3 24-hydroxylase|1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial|24-OHase|cytochrome P450 24A1|cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)|cytochrome P450-CC24|exo-mitochondrial protein|vitamin D 24-hydroxylase|vitamin D(3) 24-hydroxylase
Swissprots Q15807 Q07973 Q5I2W7 Q32ML3
Accessions AAB03776 EAW75573 Q07973 AI400154 AW022349 AY858838 AAW50795 BC109083 AAI09084 BC109084 AAI09085 BI491491 BM928702 BU662901 CN311231 L13286 AAA62379 N29030 S67623 AAB29308 XM_005260304 XP_005260361 NM_000782 NP_000773 NM_001128915 NP_001122387
Function Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Subcellular Location Mitochondrion.
Top Pathways MicroRNAs in cancer, Steroid biosynthesis

CYP24 CRISPR/Cas9 KO Plasmid (h) - sc-401233 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 HDR Plasmid (h) - sc-401233-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 Double Nickase Plasmid (h) - sc-401233-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 Double Nickase Plasmid (h2) - sc-401233-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 CRISPR Activation Plasmid (h) - sc-401233-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 CRISPR Activation Plasmid (h2) - sc-401233-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 Lentiviral Activation Particles (h) - sc-401233-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 Lentiviral Activation Particles (h2) - sc-401233-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP24 siRNA (h) - sc-44652 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP24 shRNA Plasmid (h) - sc-44652-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP24 shRNA (h) Lentiviral Particles - sc-44652-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP24A1 RNAi - H00001591-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU002561 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN6877 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6877 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08785 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08785

CYP24A1 siRNA (Human) - CRH1118 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP24A1 - MBS8224423 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CYP24A1 (NM_000782.4) - SHH272921 from Creative biogene

Category siRNA
Species Reactivities Human

Human CYP24A1 siRNA - orb261620 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP24A1 shRNA Plasmid (Human) - CHH1118 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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