BAG4

Gene Symbol BAG4
Entrez Gene 9530
Alt Symbol BAG-4, SODD
Species Human
Gene Type protein-coding
Description BCL2-associated athanogene 4
Other Description BAG family molecular chaperone regulator 4|BAG-family molecular chaperone regulator-4|bcl-2-associated athanogene 4|silencer of death domains
Swissprots O95818 B4E217 O95429
Accessions EAW63330 EAW63331 O95429 AF095194 AAD16123 AF111116 AAD05226 AI640615 AK304072 BAG64979 AK314020 BAG36731 AL049466 BC000800 BC038505 AAH38505 BM683128 NM_001204878 NP_001191807 NM_004874 NP_004865
Function Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria. {ECO:0000250, ECO:0000269|PubMed:24270810}.
Subcellular Location Cytoplasm.
Tissue Specificity Ubiquitous.
Top Pathways TNF signaling pathway

SODD (C-12) - sc-166581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SODD (C-12): sc-166581. Western blot analysis of SODD expression in H4 whole cell lysate.

SODD (H-300) - sc-8980 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SODD (H-300): sc-8980. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing nuclear and cytoplasmic staining of glandular cells.

SODD (N-19) - sc-9179 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SODD (N-19): sc-9179. Western blot analysis of SODD expression in HeLa whole cell lysate.

Anti-Silencer of Death Domain antibody - ab2048 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Silencer of Death Domain antibody (ab2048) at 1/500 dilutionLane 1 : HeLa whole cell lysate with absence of blocking peptideLane 2 : THP-1 whole cell lysate with absence of blocking peptideLane 3 : HeLa whole cell lysate with Silencer of Death Domain peptide (ab8382)Lane 4 : THP-1 whole cell lysate with Silencer of Death Domain peptide (ab8382)Observed band size : 60 kDa (why is the actual band size different from the predicted?)

Anti-Silencer of Death Domain antibody - ab88497 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Silencer of Death Domain antibody (ab88497) at 1 µg/ml + human pancreas tissue lysate at 50 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-Silencer of Death Domain antibody - ab189177 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-Silencer of Death Domain antibody (ab189177) at 1 µg/ml + HEK293 lysate (in RIPA buffer) at 35 µg

Anti-Silencer of Death Domain antibody - ab115843 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with ab115843 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Silencer of Death Domain antibody - ab124198 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Silencer of Death Domain antibody (ab124198) at 1/100 dilution + HeLa cell line lysates at 35 µg

Anti-Silencer of Death Domain antibody [EPR3596] - ab108988 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3596
All lanes : Anti-Silencer of Death Domain antibody [EPR3596] (ab108988) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysateLane 3 : Molt-4 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit IgG at 1/2000 dilution

Anti-Silencer of Death Domain antibody [EPR3597] - ab134051 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3597
All lanes : Anti-Silencer of Death Domain antibody [EPR3597] (ab134051) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : MOLT4 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Silencer of Death Domain antibody - C-terminal - ab189632 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-cardiac Troponin I antibody (ab1000) at 1/189632 dilution + Mouse thymus tissue lysate

Anti-BAG4 / SODD Antibody (Internal, clone EPR3596) - LS-C137928 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3596
Immunofluorescent staining of HeLa cells using anti-SODD antibody.

Anti-BAG4 / SODD Antibody (Internal, clone EPR3597) - LS-C137935 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3597
IHC of paraffin-embedded human kidney tissue using anti-SODD antibody.

Anti-BAG4 / SODD Antibody (aa349-363) IHC-plus™ - LS-B8303 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SODD / BAG4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8303 dilution 3.75 ug/ml.

Anti-BAG4 / SODD Antibody (N-Terminus) IHC-plus™ - LS-B446 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BAG4 / SODD antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B446 concentration 5 ug/ml.

Anti-BAG4 / SODD Antibody (aa122-457) - LS-C39166 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BAG4 / SODD Antibody (aa1-457) - LS-C39167 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BAG4 / SODD Antibody (N-Terminus) - LS-C48262 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BAG4 / SODD Antibody (aa443-457) - LS-C19336 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of 30 ug of total cell lysate from HeLa cells with anti-SODD (antibody) at 2 ug/ml.

Anti-BAG4 / SODD Antibody - LS-C26614 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of anti-SODD (NT) antibody on HeLa (1,3) and THP-1 (2,4) whole cell lysates in the absence (1,2) and presence (3,4) of blocking peptide.

Anti-BAG4 / SODD Antibody (aa223-241) - LS-C148219 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG4 / SODD Antibody (N-Terminus) - LS-C189205 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-BAG4 / SODD Antibody (Val442) - LS-C193179 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BAG4 / SODD Antibody (aa380-409, AP) - LS-C212915 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAG4 / SODD Antibody (aa380-409, Biotin) - LS-C212916 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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