| Gene Symbol |
BAG4
|
| Entrez Gene |
9530
|
| Alt Symbol |
BAG-4, SODD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BCL2-associated athanogene 4
|
| Other Description |
BAG family molecular chaperone regulator 4|BAG-family molecular chaperone regulator-4|bcl-2-associated athanogene 4|silencer of death domains
|
| Swissprots |
O95818 B4E217 O95429
|
| Accessions |
EAW63330 EAW63331 O95429 AF095194 AAD16123 AF111116 AAD05226 AI640615 AK304072 BAG64979 AK314020 BAG36731 AL049466 BC000800 BC038505 AAH38505 BM683128 NM_001204878 NP_001191807 NM_004874 NP_004865
|
| Function |
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria. {ECO:0000250, ECO:0000269|PubMed:24270810}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
TNF signaling pathway
|