Gene Symbol | Socs2 |
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Entrez Gene | 84607 |
Alt Symbol | Cish2, Socs-2 |
Species | Rat |
Gene Type | protein-coding |
Description | suppressor of cytokine signaling 2 |
Other Description | cytokine inducible SH2-containing protein 2|cytokine-inducible SH2 protein 2 |
Swissprots | O88582 |
Accessions | CAB64205 EDM16862 EDM16863 EDM16864 EDM16865 EDM16866 EDM16867 O88582 AF075382 AAC26222 NM_058208 NP_478115 |
Function | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). {ECO:0000250}. |
Top Pathways | Jak-STAT signaling pathway, Insulin signaling pathway, Type II diabetes mellitus, Prolactin signaling pathway |
Recombinant Suppressors Of Cytokine Signaling 2 (SOCS2) - RPH154Ra01 from Cloud-clone
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Recombinant Rat Suppressor of cytokine signaling 2(Socs2) - CSB-YP022389RA CSB-EP022389RA CSB-BP022389RA CSB-MP022389RA from Cusabio
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Recombinant Rat SOCS2 Protein - SOCS2-5664R from Creative Biomart
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SOCS2 Recombinant Protein (OPCD07095) - OPCD07095 from Aviva Systems Biology
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Suppressor of cytokine signaling 2 (Socs2), Recombinant Protein - MBS1221007 from MyBioSource
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