Gene Symbol | KLK11 |
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Entrez Gene | 11012 |
Alt Symbol | PRSS20, TLSP |
Species | Human |
Gene Type | protein-coding |
Description | kallikrein-related peptidase 11 |
Other Description | hK11|hippostasin|kallikrein 11|kallikrein-11|serine protease 20|trypsin-like protease |
Swissprots | Q8IXD7 Q9NS65 Q0WXX5 O75837 Q9UBX7 |
Accessions | AAD47815 AAG23257 AAG33364 EAW71970 EAW71971 EAW71972 Q9UBX7 AB012917 BAA33404 AB013730 BAA88713 AB041036 BAA96797 AB078780 BAC54105 AB259014 BAF02733 AB261897 BAE95335 AK308207 AY359014 AAQ89373 BC015551 BC022068 AAH22068 BG697071 HQ447348 ADQ31834 XM_005258439 XP_005258496 XM_011526369 XP_011524671 XM_011526370 XP_011524672 XM_011526371 XP_011524673 XM_011526372 XP_011524674 XM_011526373 XP_011524675 NM_001136032 NP_001129504 NM_001167605 NP_001161077 NM_006853 NP_006844 NM_144947 NP_659196 |
Function | Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. {ECO:0000269|PubMed:10872828, ECO:0000269|PubMed:16467084}. |
Subcellular Location | Isoform 1: Secreted. |
Tissue Specificity | Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level). {ECO:0000269|PubMed:10872828, ECO:0000269|PubMed:16467084}. |
KLK11 (N-13) - sc-20387 from Santa Cruz Biotechnology
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KLK11 (X212) - sc-80143 from Santa Cruz Biotechnology
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Anti-Kallikrein 11 antibody - ab152098 from Abcam
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Anti-Kallikrein 11 antibody - ab131038 from Abcam
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Anti-Kallikrein 11 antibody - ab75225 from Abcam
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Anti-Kallikrein 11 antibody [MM0427-4N39] - ab89664 from Abcam
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Anti-Kallikrein 11 antibody - Catalytic domain - ab40957 from Abcam
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Anti-Kallikrein 11 antibody - Kallikrein loop - ab28307 from Abcam
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Anti-KLK11 / Kallikrein 11 Antibody (aa68-82) - LS-C2789 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa22-250) - LS-C8327 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody - LS-C83449 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (C-Terminus) - LS-C53363 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa39-282, Biotin) - LS-C300980 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (Cleaved) - LS-C342196 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa39-282, FITC) - LS-C305618 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody - LS-C342112 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody - LS-C308575 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa35-84) - LS-C121084 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa39-282) - LS-C294969 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa233-250) - LS-C312783 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa68-82) IHC-plus⢠- LS-B2310 from LifeSpan Bioscience
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Anti-KLK11 / Kallikrein 11 Antibody (aa22-250) - LS-C8328 from LifeSpan Bioscience
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Kallikrein 11 Antibody [Unconjugated] - AF1595 from Novus Biologicals
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Kallikrein 11 Antibody (371604) - MAB15951 from Novus Biologicals
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Kallikrein 11 Antibody - 33470002 from Novus Biologicals
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