Gene Symbol | KLK11 |
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Entrez Gene | 11012 |
Alt Symbol | PRSS20, TLSP |
Species | Human |
Gene Type | protein-coding |
Description | kallikrein-related peptidase 11 |
Other Description | hK11|hippostasin|kallikrein 11|kallikrein-11|serine protease 20|trypsin-like protease |
Swissprots | Q8IXD7 Q9NS65 Q0WXX5 O75837 Q9UBX7 |
Accessions | AAD47815 AAG23257 AAG33364 EAW71970 EAW71971 EAW71972 Q9UBX7 AB012917 BAA33404 AB013730 BAA88713 AB041036 BAA96797 AB078780 BAC54105 AB259014 BAF02733 AB261897 BAE95335 AK308207 AY359014 AAQ89373 BC015551 BC022068 AAH22068 BG697071 HQ447348 ADQ31834 XM_005258439 XP_005258496 XM_011526369 XP_011524671 XM_011526370 XP_011524672 XM_011526371 XP_011524673 XM_011526372 XP_011524674 XM_011526373 XP_011524675 NM_001136032 NP_001129504 NM_001167605 NP_001161077 NM_006853 NP_006844 NM_144947 NP_659196 |
Function | Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. {ECO:0000269|PubMed:10872828, ECO:0000269|PubMed:16467084}. |
Subcellular Location | Isoform 1: Secreted. |
Tissue Specificity | Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level). {ECO:0000269|PubMed:10872828, ECO:0000269|PubMed:16467084}. |
Active human Kallikrein 11 full length protein - ab181953 from Abcam
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Human Kallikrein 11 full length protein - ab132062 from Abcam
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Human Kallikrein 11 full length protein - ab151649 from Abcam
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Human Kallikrein 11 full length protein - ab193754 from Abcam
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Kallikrein 11 peptide - ab41389 from Abcam
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Kallikrein 11 peptide - ab43093 from Abcam
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Kallikrein 11 Recombinant Protein - H00011012-P01 from Novus Biologicals
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Recombinant Human Kallikrein 11, CF - 1595-SE-010 from R&D Systems
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Human Hippostasin protein - orb83319 from Biorbyt
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Human Kallikrein 11 protein - orb49488 from Biorbyt
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Kallikrein-11 protein - orb197667 from Biorbyt
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KLK11 protein (His tag) - 80R-3906 from Fitzgerald
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Human Kallikrein 11 Protein - abx067586 from Abbexa
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Kallikrein 11 Blocking Peptide - abx064237 from Abbexa
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Kallikrein 11 Blocking Peptide - abx063719 from Abbexa
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KLK11 / Kallikrein-11 (54-278) - AR51593PU-N from Acris Antibodies
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KLK11 / Kallikrein-11 (54-278) - AR51593PU-S from Acris Antibodies
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KLK11 / Kallikrein-11 - H00011012-P01 from Acris Antibodies
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Recombinant Human Kallikrein-11 - 230-00571-10 from RayBiotech
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Recombinant Human Kallikrein-11 - 230-00571-50 from RayBiotech
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Recombinant Human Kallikrein-11 - 230-00571-100 from RayBiotech
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Kallikrein-11, Human Recombinant - 228-12529-1 from RayBiotech
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Recombinant Human Kallikrein-11 - 228-12529-2 from RayBiotech
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Recombinant Human Kallikrein-11 - 228-12529-3 from RayBiotech
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Kallikrein 11, Human, Recombinant - 19-C361 from ARP American Research Products
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