Gene Symbol | B3GALT2 |
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Entrez Gene | 8707 |
Alt Symbol | BETA3GALT2, GLCT2, beta3Gal-T2 |
Species | Human |
Gene Type | protein-coding |
Description | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
Other Description | UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2|beta-1,3-GalTase 2|beta-1,3-galactosyltransferase 2|beta-3-galt2 |
Swissprots | B2RAB1 Q9BZQ9 O43825 |
Accessions | CAJ78385 EAW91251 O43825 AF288390 AAG60610 AK314116 BAG36808 BC022507 AAH22507 DA116294 HQ447956 ADQ32440 Y15060 CAA75344 NM_003783 NP_003774 |
Function | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. {ECO:0000269|PubMed:9417100, ECO:0000269|PubMed:9582303}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in heart and brain. {ECO:0000269|PubMed:9417100, ECO:0000269|PubMed:9582303}. |
Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |
β-1,3-Gal-T2 (N-16) - sc-22271 from Santa Cruz Biotechnology
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Anti-B3GALT2 antibody - ab177736 from Abcam
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Anti-GLCT2 / B3GALT2 Antibody (aa394-422, AP) - LS-C212878 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa394-422, APC) - LS-C212879 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa394-422, Biotin) - LS-C212880 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa394-422, Azide-free, HRP) - LS-C212882 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa394-422, FITC) - LS-C212881 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa394-422, PE) - LS-C212884 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa324-422) - LS-C306469 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa393-422) - LS-C319732 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa352-401) - LS-C135180 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa373-422) - LS-C198666 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody (aa394-422) - LS-C156703 from LifeSpan Bioscience
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Anti-GLCT2 / B3GALT2 Antibody - LS-C51647 from LifeSpan Bioscience
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B3GALT2 Antibody (3A6) - H00008707-M02 from Novus Biologicals
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B3GALT2 Antibody (1D9) - H00008707-M03 from Novus Biologicals
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Monoclonal Anti-B3GALT2 antibody produced in mouse - WH0008707M2 from Sigma-Aldrich
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Anti-B3GALT2, C-Terminal antibody produced in rabbit - SAB4503458 from Sigma-Aldrich
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Anti-B3GALT2 antibody produced in rabbit - HPA055372 from Sigma-Aldrich
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Anti-B3GALT2 (409-422) antibody produced in rabbit - SAB1105049 from Sigma-Aldrich
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Monoclonal Anti-B3GALT2 antibody produced in mouse - SAB1401434 from Sigma-Aldrich
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B3GALT2-Antibody-C-term - AP14494b from Abgent, a WuXi AppTec company
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B3GALT2-Antibody-monoclonal-M02 - AT1252a from Abgent, a WuXi AppTec company
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B3galt2 antibody, C-term - GTX44689 from GeneTex
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B3GALT2 antibody - GTX118318 from GeneTex
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