| Gene Symbol |
B3GALT2
|
| Entrez Gene |
8707
|
| Alt Symbol |
BETA3GALT2, GLCT2, beta3Gal-T2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
|
| Other Description |
UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2|beta-1,3-GalTase 2|beta-1,3-galactosyltransferase 2|beta-3-galt2
|
| Swissprots |
B2RAB1 Q9BZQ9 O43825
|
| Accessions |
CAJ78385 EAW91251 O43825 AF288390 AAG60610 AK314116 BAG36808 BC022507 AAH22507 DA116294 HQ447956 ADQ32440 Y15060 CAA75344 NM_003783 NP_003774
|
| Function |
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. {ECO:0000269|PubMed:9417100, ECO:0000269|PubMed:9582303}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Detected in heart and brain. {ECO:0000269|PubMed:9417100, ECO:0000269|PubMed:9582303}.
|
| Top Pathways |
Glycosphingolipid biosynthesis - lacto and neolacto series
|
