| Gene Symbol | B3GALT2 |
|---|---|
| Entrez Gene | 8707 |
| Alt Symbol | BETA3GALT2, GLCT2, beta3Gal-T2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| Other Description | UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2|beta-1,3-GalTase 2|beta-1,3-galactosyltransferase 2|beta-3-galt2 |
| Swissprots | B2RAB1 Q9BZQ9 O43825 |
| Accessions | CAJ78385 EAW91251 O43825 AF288390 AAG60610 AK314116 BAG36808 BC022507 AAH22507 DA116294 HQ447956 ADQ32440 Y15060 CAA75344 NM_003783 NP_003774 |
| Function | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. {ECO:0000269|PubMed:9417100, ECO:0000269|PubMed:9582303}. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Tissue Specificity | Detected in heart and brain. {ECO:0000269|PubMed:9417100, ECO:0000269|PubMed:9582303}. |
| Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |