HAT1

Gene Symbol HAT1
Entrez Gene 8520
Alt Symbol KAT1
Species Human
Gene Type protein-coding
Description histone acetyltransferase 1
Other Description histone acetyltransferase type B catalytic subunit
Swissprots O14929 Q8WWB9 Q6P594 Q49A44 Q53QF0 Q53SU4
Accessions AAX93247 AAY14731 EAX11194 EAX11195 O14929 AF030424 AAC02425 AK127840 AK309001 AK313699 BC018682 AAH18682 BC045673 BC063003 AAH63003 BG184638 DB050336 HQ448051 ADQ32532 XM_006712808 XP_006712871 XM_011512027 XP_011510329 NM_003642 NP_003633 NR_027862 NM_001033085
Function Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. {ECO:0000269|PubMed:11585814, ECO:0000269|PubMed:20953179, ECO:0000269|PubMed:22615379, ECO:0000269|PubMed:9427644}.
Subcellular Location Isoform A: Nucleus matrix.
Top Pathways Alcoholism

HAT1 (H-7) - sc-390562 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HAT1 (H-7): sc-390562. Western blot analysis of HAT1 expression in BT-20 (A) and HeLa (B) whole cell lysates and HeLa nuclear extract (C).

HAT1 (B-10) - sc-376268 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HAT1 (B-10): sc-376268. Western blot analysis of HAT1 expression in HeLa (A) and BT-20 (B) whole cell lysates.

HAT1 (C-20) - sc-8752 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HAT1 (C-20): sc-8752. Western blot analysis of HAT1 expression in HeLa (A) and BT-20 (B) whole cell lysates and A-431 (C) and HeLa (D) nuclear extracts.

HAT1 (G-12) - sc-376200 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HAT1 (G-12): sc-376200. Western blot analysis of HAT1 expression in HeLa (A) and BT-20 (B) whole cell lysates.

HAT1 (H-300) - sc-366092 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HAT1 (H-300): sc-366092. Western blot analysis of HAT1 expression in BT-20 (A), HeLa (B) and Jurkat (C) whole cell lysates.

HAT1 (N-18) - sc-8751 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HAT1 (N-18): sc-8751. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

Anti-KAT1 / HAT1 antibody - ab12164 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-KAT1 / HAT1 antibody - ab61225 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KAT1 / HAT1 antibody (ab61225) at 1/500 dilutionLane 1 : extracts from LOVO cellsLane 2 : extracts from LOVO cells with immunizing peptide

Anti-KAT1 / HAT1 antibody - ab123305 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-KAT1 / HAT1 antibody (ab123305) at 1/100 dilution + HL60 cell line lysates at 35 µg

Anti-KAT1 / HAT1 antibody - C-terminal - ab135127 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-KAT1 / HAT1 antibody - C-terminal (ab135127) at 1/1000 dilution + Mouse thymus total cell extract

Anti-KAT1 / HAT1 antibody - C-terminal - ab135489 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KAT1 / HAT1 antibody - C-terminal (ab135489) at 1/50 dilutionLane 1 : 293 cell line lysateLane 2 : HepG2 cell line lysateLane 3 : Jurkat cell line lysateLysates/proteins at 35 µg per lane.

Anti-HAT1 Antibody (C-Terminus) - LS-C96627 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of hHAT1-E404 in 293, HepG2, Jurkat cell line lysates (35 ug/lane). HAT1 (arrow) was detected using the purified antibody.

Anti-HAT1 Antibody (aa21-50, AP) - LS-C258258 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (aa21-50, APC) - LS-C258259 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (aa40-89) - LS-C151246 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HAT1 antibody Western Blot of Rat Pancreas.

Anti-HAT1 Antibody (aa21-50, Biotin) - LS-C258260 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (aa21-50, FITC) - LS-C258261 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (aa21-50, PE) - LS-C258263 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (aa21-50, Azide-free, HRP) - LS-C258262 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (C-Terminus, AP) - LS-C277838 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (Ser361) - LS-C176520 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of HAT1 (S361) pAb in extracts from LOVO cells.

Anti-HAT1 Antibody (C-Terminus, APC) - LS-C277839 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (C-Terminus, Biotin) - LS-C277840 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (C-Terminus, Azide-free, HRP) - LS-C277842 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HAT1 Antibody (C-Terminus, FITC) - LS-C277841 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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