HAT1

Gene Symbol HAT1
Entrez Gene 8520
Alt Symbol KAT1
Species Human
Gene Type protein-coding
Description histone acetyltransferase 1
Other Description histone acetyltransferase type B catalytic subunit
Swissprots O14929 Q8WWB9 Q6P594 Q49A44 Q53QF0 Q53SU4
Accessions AAX93247 AAY14731 EAX11194 EAX11195 O14929 AF030424 AAC02425 AK127840 AK309001 AK313699 BC018682 AAH18682 BC045673 BC063003 AAH63003 BG184638 DB050336 HQ448051 ADQ32532 XM_006712808 XP_006712871 XM_011512027 XP_011510329 NM_003642 NP_003633 NR_027862 NM_001033085
Function Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. {ECO:0000269|PubMed:11585814, ECO:0000269|PubMed:20953179, ECO:0000269|PubMed:22615379, ECO:0000269|PubMed:9427644}.
Subcellular Location Isoform A: Nucleus matrix.
Top Pathways Alcoholism

HAT1 CRISPR/Cas9 KO Plasmid (h) - sc-402357 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 HDR Plasmid (h) - sc-402357-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 Double Nickase Plasmid (h) - sc-402357-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 Double Nickase Plasmid (h2) - sc-402357-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 CRISPR Activation Plasmid (h) - sc-402357-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 CRISPR Activation Plasmid (h2) - sc-402357-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 Lentiviral Activation Particles (h) - sc-402357-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 Lentiviral Activation Particles (h2) - sc-402357-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HAT1 siRNA (h) - sc-37948 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HAT1 shRNA Plasmid (h) - sc-37948-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HAT1 shRNA (h) Lentiviral Particles - sc-37948-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KAT1 RNAi - H00008520-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KAT1 RNAi - H00008520-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU034621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1586 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1586 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02660 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02660

HAT1 siRNA (Human) - CRH5593 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HAT1 - MBS8239183 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HAT1 (NM_003642.3) - SHH310405 from Creative biogene

Category siRNA
Species Reactivities Human

Human HAT1 siRNA - orb266095 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HAT1 shRNA Plasmid (Human) - CHH5593 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HAT1 miRNA 3'UTR clone - MiUTR3H-05599 from Creative biogene

Species Reactivities Human
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