| Gene Symbol | GPHB5 |
|---|---|
| Entrez Gene | 122876 |
| Alt Symbol | B5, GPB5, ZLUT1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | glycoprotein hormone beta 5 |
| Other Description | glycoprotein beta 5|glycoprotein hormone beta subunit|glycoprotein hormone beta-5|thyrostimulin subunit beta |
| Swissprots | Q86YW7 Q6NTD0 Q8NFW2 |
| Accessions | CAJ32902 CAM33586 EAW80825 Q86YW7 AF403430 AAM53261 AF467770 AAO33390 BC069113 AAH69113 BC133702 AAI33703 BM709443 NM_145171 NP_660154 |
| Function | Stimulates the thyroid. Binds and activates THSR, leading to increased cAMP production. {ECO:0000269|PubMed:12045258, ECO:0000269|PubMed:16210345}. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting that it is located in corticotrophs. {ECO:0000269|PubMed:12089349, ECO:0000269|PubMed:16210345}. |
Panoply™ Human GPHB5 Knockdown Stable Cell Line - CSC-DC006494 from Creative biogene
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