GPHB5

Gene Symbol GPHB5
Entrez Gene 122876
Alt Symbol B5, GPB5, ZLUT1
Species Human
Gene Type protein-coding
Description glycoprotein hormone beta 5
Other Description glycoprotein beta 5|glycoprotein hormone beta subunit|glycoprotein hormone beta-5|thyrostimulin subunit beta
Swissprots Q86YW7 Q6NTD0 Q8NFW2
Accessions CAJ32902 CAM33586 EAW80825 Q86YW7 AF403430 AAM53261 AF467770 AAO33390 BC069113 AAH69113 BC133702 AAI33703 BM709443 NM_145171 NP_660154
Function Stimulates the thyroid. Binds and activates THSR, leading to increased cAMP production. {ECO:0000269|PubMed:12045258, ECO:0000269|PubMed:16210345}.
Subcellular Location Secreted.
Tissue Specificity Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting that it is located in corticotrophs. {ECO:0000269|PubMed:12089349, ECO:0000269|PubMed:16210345}.

Human GPHB5 ORF Clone(NM_145171.3) - CDCL165098 from Creative Biomart

Species Human
Accession NM_145171.3
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