CLCN7

Gene Symbol CLCN7
Entrez Gene 1186
Alt Symbol CLC-7, CLC7, OPTA2, OPTB4, PPP1R63
Species Human
Gene Type protein-coding
Description chloride channel, voltage-sensitive 7
Other Description H(+)/Cl(-) exchange transporter 7|chloride channel 7 alpha subunit|chloride channel protein 7|protein phosphatase 1, regulatory subunit 63
Swissprots P51798 E9PDB9 A8K7X1 B3KPN3 Q9NYX5 A8K5T9 A6NEJ7
Accessions AAK61282 CAA05083 EAW85653 EAW85654 EAW85655 P51798 AA741117 AF224741 AAF34711 AI684019 AK056551 BAG51745 AK096963 BAG53401 AK122944 BAG53810 AK128285 BAG54655 AK130196 AK291404 BAF84093 AK292136 BAF84825 AK304796 BAG65546 AK315978 BAH14349 BC004946 AAH04946 BC006158 AAH06158 BC012737 AAH12737 BC015235 BC109196 AAI09197 DB061109 DQ896433 ABM87432 EU176438 ABW03889 U88844 AAB48530 Z67743 CAA91556 XM_011522354 XP_011520656 NM_001114331 NP_001107803 NM_001287 NP_001278
Function Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen. {ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}; Multi-pass membrane protein {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}.
Tissue Specificity Brain, testis, muscle and kidney.

CLC-7 (H-90) - sc-28755 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CLC-7 (H-90): sc-28755. Western blot analysis of CLC-7 expression in NTERA-2 cl.D1 whole cell lysate.

CLC-7 (C-15) - sc-16444 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CLC-7 (N-20) - sc-16442 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CLC7 antibody - ab86196 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-CLC7 antibody - ab136016 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CLC7 antibody (ab136016) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-CLC7 antibody - C-terminal - ab170502 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of WiDr cells labeling CLC7 with ab170502 at 1/10 followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green) and DAPI staining.

Anti-CLC7 antibody - C-terminal - ab194433 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-CLC7 antibody - C-terminal (ab194433) at 1/500 dilution + HL60 cell lysate at 50 µg

Anti-CLC-7 / CLCN7 Antibody (C-Terminus) - LS-C6136 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (C-Terminus) - LS-C6137 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (N-Terminus) - LS-C6138 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (N-Terminus) - LS-C6139 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (clone 4A3) - LS-C196932 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4A3

Anti-CLC-7 / CLCN7 Antibody (aa699-728, AP) - LS-C254939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa699-728, Biotin) - LS-C254941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa699-728, APC) - LS-C254940 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa699-728, Azide-free, HRP) - LS-C254943 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa699-728, FITC) - LS-C254942 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa23-72) - LS-C291808 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa699-728, PE) - LS-C254945 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa10-59) - LS-C291308 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa699-728) - LS-C320417 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody (aa33-78) - LS-C313714 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLC-7 / CLCN7 Antibody - LS-C346131 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using CLCN7 antibody. Blue: DAPI for nuclear staining.

Anti-CLC-7 / CLCN7 Antibody (aa699-728) - LS-C168806 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CLCN7 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

CLCN7 Antibody - NBP1-30854 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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