CLCN7

Gene Symbol CLCN7
Entrez Gene 1186
Alt Symbol CLC-7, CLC7, OPTA2, OPTB4, PPP1R63
Species Human
Gene Type protein-coding
Description chloride channel, voltage-sensitive 7
Other Description H(+)/Cl(-) exchange transporter 7|chloride channel 7 alpha subunit|chloride channel protein 7|protein phosphatase 1, regulatory subunit 63
Swissprots P51798 E9PDB9 A8K7X1 B3KPN3 Q9NYX5 A8K5T9 A6NEJ7
Accessions AAK61282 CAA05083 EAW85653 EAW85654 EAW85655 P51798 AA741117 AF224741 AAF34711 AI684019 AK056551 BAG51745 AK096963 BAG53401 AK122944 BAG53810 AK128285 BAG54655 AK130196 AK291404 BAF84093 AK292136 BAF84825 AK304796 BAG65546 AK315978 BAH14349 BC004946 AAH04946 BC006158 AAH06158 BC012737 AAH12737 BC015235 BC109196 AAI09197 DB061109 DQ896433 ABM87432 EU176438 ABW03889 U88844 AAB48530 Z67743 CAA91556 XM_011522354 XP_011520656 NM_001114331 NP_001107803 NM_001287 NP_001278
Function Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen. {ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}; Multi-pass membrane protein {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}.
Tissue Specificity Brain, testis, muscle and kidney.

CLC-7 CRISPR/Cas9 KO Plasmid (h) - sc-404550 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 HDR Plasmid (h) - sc-404550-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 Double Nickase Plasmid (h) - sc-404550-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 Double Nickase Plasmid (h2) - sc-404550-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 CRISPR Activation Plasmid (h) - sc-404550-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 CRISPR Activation Plasmid (h2) - sc-404550-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 Lentiviral Activation Particles (h) - sc-404550-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 Lentiviral Activation Particles (h2) - sc-404550-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 siRNA (h) - sc-42389 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLC-7 shRNA Plasmid (h) - sc-42389-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLC-7 shRNA (h) Lentiviral Particles - sc-42389-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLCN7 RNAi - H00001186-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU052231 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1975 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1975 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLCN7 siRNA (Human) - CRH0848 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLCN7 - MBS8239966 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLC-7 CRISPR/Cas9 KO Plasmid (h2) - sc-404550-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-7 HDR Plasmid (h2) - sc-404550-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human CLCN7 siRNA - orb261350 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLCN7 shRNA Plasmid (Human) - CHH0848 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLCN7 miRNA 3'UTR clone - MiUTR3H-05268 from Creative biogene

Species Reactivities Human

CLCN7 miRNA 3'UTR clone - MiUTR3H-05269 from Creative biogene

Species Reactivities Human
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