Gene Symbol | CLCN7 |
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Entrez Gene | 1186 |
Alt Symbol | CLC-7, CLC7, OPTA2, OPTB4, PPP1R63 |
Species | Human |
Gene Type | protein-coding |
Description | chloride channel, voltage-sensitive 7 |
Other Description | H(+)/Cl(-) exchange transporter 7|chloride channel 7 alpha subunit|chloride channel protein 7|protein phosphatase 1, regulatory subunit 63 |
Swissprots | P51798 E9PDB9 A8K7X1 B3KPN3 Q9NYX5 A8K5T9 A6NEJ7 |
Accessions | AAK61282 CAA05083 EAW85653 EAW85654 EAW85655 P51798 AA741117 AF224741 AAF34711 AI684019 AK056551 BAG51745 AK096963 BAG53401 AK122944 BAG53810 AK128285 BAG54655 AK130196 AK291404 BAF84093 AK292136 BAF84825 AK304796 BAG65546 AK315978 BAH14349 BC004946 AAH04946 BC006158 AAH06158 BC012737 AAH12737 BC015235 BC109196 AAI09197 DB061109 DQ896433 ABM87432 EU176438 ABW03889 U88844 AAB48530 Z67743 CAA91556 XM_011522354 XP_011520656 NM_001114331 NP_001107803 NM_001287 NP_001278 |
Function | Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen. {ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}; Multi-pass membrane protein {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18449189, ECO:0000269|PubMed:21527911}. |
Tissue Specificity | Brain, testis, muscle and kidney. |
Human CLC7 peptide - ab32492 from Abcam
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Human CLC7 protein fragment - ab152283 from Abcam
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CLC-7 / CLCN7 Antibody Blocking Peptide - LS-E1273 from LifeSpan Bioscience
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CLCN7 Partial Recombinant Protein - H00001186-Q01 from Novus Biologicals
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CLCN7-Antibody-C-term-Blocking-peptide - BP11863b from Abgent, a WuXi AppTec company
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CLCN7 Blocking Peptide - abx062436 from Abbexa
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CLCN7 - H00001186-Q01-10 from Acris Antibodies
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CLCN7 - H00001186-Q01-25 from Acris Antibodies
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CLCN7 fusion protein - Ag14130 from Proteintech Group
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CLCN7 fusion protein - Ag14415 from Proteintech Group
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Recombinant Human CLCN7, GST-tagged - CLCN7-11280H from Creative Biomart
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CLCN7 Blocking Peptide - CBP1242 from Cohesion Biosciences
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CLCN7 Peptide - BS5664P from Bioworld Technology
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CLC7, Peptide - MBS659902 from MyBioSource
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CLCN7 Recombinant Protein Antigen - NBP1-91792PEP from Novus Biologicals
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CLCN7 Recombinant Protein Antigen - NBP1-91791PEP from Novus Biologicals
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CLCN7 Peptide, Human - M34GP03220H from Creative Peptides
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CLCN7 peptide - orb217105 from Biorbyt
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H (+)/Cl (-) exchange transporter 7 (CLCN7), Recombinant Protein - MBS961643 from MyBioSource
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