AKR1B10

Gene Symbol	AKR1B10
Entrez Gene	57016
Alt Symbol	AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member B10 (aldose reductase)
Other Description	ARP|SI reductase|aldo-keto reductase family 1 member B10|aldo-keto reductase family 1, member B11 (aldose reductase-like)|aldose reductase-like 1|aldose reductase-like peptide|aldose reductase-related protein|hARP|small intestine reductase
Swissprots	O60218 A4D1P1 O75890 Q8IWZ1 Q6FHF3
Accessions	EAL24069 EAW83816 O60218 AF044961 AAC15671 AF052577 AAC36465 AF524864 AAO13380 BC008837 AAH08837 BM975664 BT006794 AAP35440 CR541801 CAG46600 DQ890678 ABM81604 EU176471 ABW03272 U37100 AAC17469 XM_011516416 XP_011514718 XM_011516417 XP_011514719 XR_927491 NM_020299 NP_064695
Function	Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. {ECO:0000269|PubMed:18087047}.
Subcellular Location	Lysosome {ECO:0000269|PubMed:21585341}. Secreted {ECO:0000269|PubMed:21585341}. Note=Secreted through a lysosome-mediated non-classical pathway.
Tissue Specificity	Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Top Pathways	Pentose and glucuronate interconversions, Glycerolipid metabolism, Galactose metabolism, Fructose and mannose metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human AKR1B10 full length protein - ab168014 from Abcam Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

Human AKR1B10 full length protein - ab85415 from Abcam Category Protein Prices $188.00 Sizes 50 µg Source E. coli Species Human

Human AKR1B10 full length protein - ab117185 from Abcam Category Protein Prices $188.00 Sizes 5 µg Source E. coli Species Human

Human AKR1B10 peptide - ab97989 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

AKR1B10 Antibody Blocking Peptide - LS-E2995 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AKR1B10 Antibody Blocking Peptide - LS-E15669 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AKR1B10 Antibody Blocking Peptide - LS-E26619 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARL1 Antibody Blocking Peptide - LS-E4475 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARL1 Antibody Blocking Peptide - LS-E23352 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARL1 Antibody Blocking Peptide - LS-E23353 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARL1 Antibody Blocking Peptide - LS-E6935 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Aldo-keto Reductase 1B10/AKR1B10 Protein - NBC1-26377 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

ARL1 Recombinant Protein - H00000400-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Aldo-keto Reductase 1B10/AKR1B10 Recombinant Protein - H00057016-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Aldo-keto Reductase 1B10/AKR1B10 Partial Recombinant Protein - H00057016-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ARL1 Partial Recombinant Protein - H00000400-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ARL1 Protein - NBP1-45312 from Novus Biologicals Category Protein Species Human

Aldo-keto Reductase 1B10/AKR1B10 Recombinant Protein - P3486 from Novus Biologicals Category Protein Prices $669.00 Sizes 100 µg Species Human

ARL1 Peptide - P1033 from Novus Biologicals Category Peptide Species Human

AKR1B10-Antibody-Center-Blocking-peptide - BP14125c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AKR1B10 Protein - GTX109571-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

AKR1B10 blocking peptide - GTX88827-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human Aldo-keto Reductase 1B10/AKR1B10, CF - 7529-DH-020 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Ala2-Tyr316, with an N-terminal Met and 6-His tag

AKR1B10 Protein (OPPA02048) - OPPA02048 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human AKR1B10 protein - orb90021 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli Species Human

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