FST

Gene Symbol	FST
Entrez Gene	10468
Alt Symbol	FS
Species	Human
Gene Type	protein-coding
Description	follistatin
Other Description	activin-binding protein\|follistatin isoform FST317
Swissprots	Q9BTH0 B5BU94 P19883
Accessions	AAA35851 EAW54880 EAW54881 EAW54882 EAW54883 P19883 AB451330 BAG70144 AB451474 BAG70288 BC004107 AAH04107 BQ941144 BQ949678 CR541813 CAG46612 DQ893433 ABM84359 DQ896745 ABM87744 DR760015 XM_005248400 XP_005248457 XM_005248401 XP_005248458 XM_005248402 XP_005248459 XM_005248403 XP_005248460 XM_011543099 XP_011541401 NM_006350 NP_006341 NM_013409 NP_037541
Function	Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
Subcellular Location	Secreted.
Tissue Specificity	Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. {ECO:0000269\|PubMed:15472207}.
Top Pathways	TGF-beta signaling pathway

follistatin (C-8) - sc-365003 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

follistatin (C-8): sc-365003. Western blot analysis of follistatin expression in non-transfected: sc-117752 (A) and human follistatin transfected: sc-159980 (B) 293T whole cell lysates.

follistatin (D-12) - sc-271502 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

follistatin (D-12): sc-271502. Western blot analysis of follistatin expression in non-transfected: sc-117752 (A) and human follistatin transfected: sc-159980 (B) 293T whole cell lysates.

follistatin (K-19) - sc-23553 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

follistatin (K-19): sc-23553. Western blot analysis of mouse recombinant follistatin.

follistatin (H-114) - sc-30194 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

follistatin (H-114): sc-30194. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

Anti-Follistatin antibody - ab47941 from Abcam

Prices	$379.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

ICC/IF image of ab47941 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab47941 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Follistatin antibody - ab89515 from Abcam

Host	Mouse
Clonality	Monoclonal

Anti-Follistatin antibody (ab89515) at 1/500 dilution + immunogen (full length protein with a tag of 26kDa) at 0.2 µg

Anti-Follistatin antibody (Biotin) - ab47942 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Follistatin antibody [EPR10903] - ab157471 from Abcam

Prices	$379.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR10903

All lanes : Anti-Follistatin antibody [EPR10903] (ab157471) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : C6 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Follistatin antibody [MM0296-9D28] - ab89556 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	MM0296-9D28

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling Follistatin with ab89556. Tissue was treated with 15µg/ml Protenase K for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

Anti-FST / Follistatin Antibody (Biotin) - LS-C104465 from LifeSpan Bioscience

Prices	$285.00, $325.00
Sizes	25 µg, 50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (Biotin) - LS-C129178 from LifeSpan Bioscience

Prices	$650.00
Sizes	50 µg
Host	Goat
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (C-Terminus) - LS-C31897 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (C-Terminus, clone H10) - LS-C188571 from LifeSpan Bioscience

Prices	$940.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	H10

Anti-FST / Follistatin Antibody (clone 17/2) - LS-C188572 from LifeSpan Bioscience

Prices	$915.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	17/2

Anti-FST / Follistatin Antibody (Arg163) - LS-C193231 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (aa311-340, APC) - LS-C214377 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (aa311-340, AP) - LS-C214375 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (aa311-340, FITC) - LS-C214378 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (aa30-329) - LS-C149948 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Follistatin Inhibition of Activin A-induced Hemoglobin Expression and Neutralization by Human Follistatin Antibody. Recombinant Human Follistatin 300 inhibits Recombinant Human/Mouse/Rat Activin A induced hemoglobin expression in the K562 human chronic myelogenous leukemia cell line in a dose-dependent manner (orange line), as measured by psuedoperoxidase activity. Inhibition of Recombinant Human/Mouse/Rat Activin A (7.5 ng/ml) activity elicited by Recombinant Human Follistatin 300 (0.4 ug/ml) is neutralized (green line) by increasing concentrations of Goat Anti-Human Follistatin Antigen Affinity-purified Polyclonal Antibody. At 6 ug/m L, this antibody will neutralize approximately 60-85% of rhFollistatin 300 bioactivity.

Anti-FST / Follistatin Antibody (aa144-193) - LS-C110679 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

FST / Follistatin antibody LS-C110679 Western blot of Fetal Heart lysate.

Anti-FST / Follistatin Antibody (aa311-340, Azide-free, HRP) - LS-C214379 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (aa311-340, PE) - LS-C214381 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FST / Follistatin Antibody (aa30-329, clone 85918) - LS-C149949 from LifeSpan Bioscience

Prices	$385.00
Sizes	500 µg
Host	Mouse
Clonality	Monoclonal
Clone	85918

Follistatin in Human Pituitary. Follistatin was detected in immersion fixed paraffin-embedded sections of human pituitary using Human Follistatin Monoclonal Antibody at 25 ug/ml overnight at 4°C. Tissue was stained using Anti-Mouse HRP-DAB (brown) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents.

Anti-FST / Follistatin Antibody - LS-C48951 from LifeSpan Bioscience

Prices	$410.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Follistatin antibody LS-C48951.

Anti-FST / Follistatin Antibody (aa114-163) - LS-C291970 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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