Gene Symbol | FST |
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Entrez Gene | 10468 |
Alt Symbol | FS |
Species | Human |
Gene Type | protein-coding |
Description | follistatin |
Other Description | activin-binding protein|follistatin isoform FST317 |
Swissprots | Q9BTH0 B5BU94 P19883 |
Accessions | AAA35851 EAW54880 EAW54881 EAW54882 EAW54883 P19883 AB451330 BAG70144 AB451474 BAG70288 BC004107 AAH04107 BQ941144 BQ949678 CR541813 CAG46612 DQ893433 ABM84359 DQ896745 ABM87744 DR760015 XM_005248400 XP_005248457 XM_005248401 XP_005248458 XM_005248402 XP_005248459 XM_005248403 XP_005248460 XM_011543099 XP_011541401 NM_006350 NP_006341 NM_013409 NP_037541 |
Function | Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). |
Subcellular Location | Secreted. |
Tissue Specificity | Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. {ECO:0000269|PubMed:15472207}. |
Top Pathways | TGF-beta signaling pathway |
follistatin CRISPR/Cas9 KO Plasmid (h) - sc-401687 from Santa Cruz Biotechnology
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follistatin HDR Plasmid (h) - sc-401687-HDR from Santa Cruz Biotechnology
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follistatin Double Nickase Plasmid (h) - sc-401687-NIC from Santa Cruz Biotechnology
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follistatin Double Nickase Plasmid (h2) - sc-401687-NIC-2 from Santa Cruz Biotechnology
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follistatin CRISPR Activation Plasmid (h) - sc-401687-ACT from Santa Cruz Biotechnology
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follistatin CRISPR Activation Plasmid (h2) - sc-401687-ACT-2 from Santa Cruz Biotechnology
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follistatin Lentiviral Activation Particles (h) - sc-401687-LAC from Santa Cruz Biotechnology
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follistatin Lentiviral Activation Particles (h2) - sc-401687-LAC-2 from Santa Cruz Biotechnology
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follistatin siRNA (h) - sc-39762 from Santa Cruz Biotechnology
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follistatin shRNA Plasmid (h) - sc-39762-SH from Santa Cruz Biotechnology
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follistatin shRNA (h) Lentiviral Particles - sc-39762-V from Santa Cruz Biotechnology
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Follistatin RNAi - H00010468-R02 from Novus Biologicals
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Follistatin RNAi - H00010468-R01 from Novus Biologicals
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MISSION® esiRNA - EHU051831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8970 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8970 from Sigma-Aldrich
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FST siRNA (Human) - CRH7106 from Cohesion Biosciences
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FST - MBS8202205 from MyBioSource
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shRNA set against Human FST (NM_006350.3) - SHH297421 from Creative biogene
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FST shRNA Plasmid (Human) - CHH7106 from Cohesion Biosciences
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FST miRNA 3'UTR clone - MiUTR4H-TG03650 from Creative biogene
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