Gene Symbol | FST |
---|---|
Entrez Gene | 10468 |
Alt Symbol | FS |
Species | Human |
Gene Type | protein-coding |
Description | follistatin |
Other Description | activin-binding protein|follistatin isoform FST317 |
Swissprots | Q9BTH0 B5BU94 P19883 |
Accessions | AAA35851 EAW54880 EAW54881 EAW54882 EAW54883 P19883 AB451330 BAG70144 AB451474 BAG70288 BC004107 AAH04107 BQ941144 BQ949678 CR541813 CAG46612 DQ893433 ABM84359 DQ896745 ABM87744 DR760015 XM_005248400 XP_005248457 XM_005248401 XP_005248458 XM_005248402 XP_005248459 XM_005248403 XP_005248460 XM_011543099 XP_011541401 NM_006350 NP_006341 NM_013409 NP_037541 |
Function | Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). |
Subcellular Location | Secreted. |
Tissue Specificity | Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. {ECO:0000269|PubMed:15472207}. |
Top Pathways | TGF-beta signaling pathway |