MYB

Gene Symbol MYB
Entrez Gene 4602
Alt Symbol Cmyb, c-myb, c-myb_CDS, efg
Species Human
Gene Type protein-coding
Description v-myb avian myeloblastosis viral oncogene homolog
Other Description c-myb protein (140 AA)|c-myb10A_CDS|c-myb13A_CDS|c-myb14A_CDS|c-myb8B_CDS|proto-oncogene c-Myb|transcriptional activator Myb
Swissprots P78392 Q708E7 Q708E4 Q14024 P78525 Q9UE83 E9PI07 P78391 E9PNL6 E9PNA4 E9PRS2 P10242 E9PLZ5 Q14023 P78526
Accessions AAA72118 AAB49034 AAB49035 AAB49036 AAB49037 AAB49038 AAB49039 ADL14499 CAS01767 CBX51725 EAW47967 EAW47968 EAW47969 EAW47970 EAW47971 EAW47972 EAW47973 EAW47974 EAW47975 EAW47976 EAW47977 EAW47978 P10242 AF104863 AAC96326 AJ606317 CAE55168 AJ606318 CAE55169 AJ606319 CAE55170 AJ606320 CAE55171 AJ606321 CAE55172 AJ606322 CAE55173 AJ606323 CAE55174 AJ606324 CAE55175 AJ616235 CAE82649 AJ616791 CAF04477 AJ616792 AJ616793 AJ616794 AJ616795 AJ616796 AJ616797 AJ616798 AJ616799 AJ616800 AJ616801 AJ616802 AJ616803 AJ616804 AJ616805 AY787443 AY787444 AY787445 AY787446 AY787447 AY787448 AY787449 AY787450 AY787451 AY787452 AY787453 AY787454 AY787455 AY787456 AY787457 AY787458 AY787459 AY787460 AY787461 AY787462 AY787463 AY787464 AY787465 AY787466 AY787467 AY787468 AY787469 AY787470 AY787471 AY787472 AY787473 AY787474 AY787475 BC035996 BC064955 AAH64955 D25774 M13665 AAA52030 M13666 AAA52031 M15024 AAA52032 X17469 CAA35503 X52125 CAA36371 X52126 CAA36372 XR_942443 XR_942444 XR_942445 XR_942446 NM_001130172 NP_001123644 NM_001130173 NP_001123645 NM_001161656 NP_001155128 NM_001161657 NP_001155129 NM_001161658 NP_001155130 NM_001161659 NP_001155131 NM_001161660 NP_001155132 NM_005375 NP_005366
Function Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00625, ECO:0000269|PubMed:19646965}.
Top Pathways HTLV-I infection, PI3K-Akt signaling pathway

c-Myb (D2R4Y) Rabbit mAb - 12319 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2R4Y
Western blot analysis of extracts from Jurkat and MOLT-4 cells using c-Myb (D2R4Y) Rabbit mAb.

c-Myb (C-19) - sc-517 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Myb (C-19): sc-517. Western blot analysis of human recombinant c-Myb fusion protein.

c-Myb (D-7) - sc-74512 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Myb (D-7): sc-74512. Western blot analysis of c-Myb expression in COLO 320DM (A) and BT-20 (B) whole cell lysates.

c-Myb (H-141) - sc-7874 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Myb (H-141): sc-7874. Western blot analysis of c-Myb expression in HL-60 whole cell lysate.

c-Myb (M-19) - sc-516 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Myb (M-19): sc-516. Western blot analysis of c-Myb expression in F9 whole cell lysate.

v-Myb/c-Myb (3H2746) - sc-73247 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
v-Myb/c-Myb (3H2746): sc-73247. Western blot analysis of v-Myb/c-Myb expression in Jurkat (A) and CCRF-CEM (B) nuclear extracts.

v-Myb/c-Myb (3H2747) - sc-73248 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
v-Myb/c-Myb (3H2747): sc-73248. Western blot analysis of c-Myb expression in Jurkat whole cell lysate.

v-Myb/c-Myb (4E3) - sc-56809 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
c-Myb (4E3): sc-56809. Western blot analysis of c-Myb expression in Jurkat (A) and CCRF-CEM (B) nuclear extracts.

v-Myb/c-Myb (SPM175) - sc-56608 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
c-Myb (SPM175): sc-56608. Western blot analysis of c-Myb expression in Jurkat (A) and CCRF-CEM (B) nuclear extracts.

Anti-c-Myb (phospho S532) antibody - ab111339 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using ab111339 at a dilution of 1/50. Left panel shows staining without immunizing peptide right panel shows staining with immunizing peptide.

Anti-c-Myb antibody - ab117635 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-c-Myb antibody (ab117635) at 1/500 dilutionLane 1 : HUVEC cell lysateLane 2 : HUVEC cell lysate with synthetic peptide

Anti-c-Myb antibody - ab59233 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Staining of C-Myb in human breast carcinoma tissue (paraffin section) with ab59233 (1/50 dilution) by Immunohistochemistry; in the absence or presence of the immunizing peptide.

Anti-c-Myb antibody - ab79551 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-c-Myb antibody (ab79551) at 1/500 dilutionLane 1 : 293 cell extractsLane 2 : 293 cell extracts with immunizing peptide at 10 µgLysates/proteins at 10 µg per lane.

Anti-c-Myb antibody - ab109633 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-c-Myb antibody (ab109633) at 1 µg/mlLane 1 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 2 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-c-Myb antibody - ab116651 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-c-Myb antibody (ab116651) at 1/100 dilution + NCI-H292 cell lysate at 35 µg

Anti-c-Myb antibody - ab76767 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-c-Myb antibody (ab76767) at 1/500 dilutionLane 1 : c-Myb transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-c-Myb antibody [1279CT309.289.119] - ab191296 from Abcam

Prices $376.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 1279CT309.289.119
Anti-c-Myb antibody [1279CT309.289.119] (ab191296) at 1/1000 dilution + CEM cell lysate at 35 µgSecondaryGoat anti-mouse IgG H&L(HRP) at 1/3000 dilution

Anti-c-Myb antibody [EPR718(2)] - ab109127 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR718(2)
All lanes : Anti-c-Myb antibody [EPR718(2)] (ab109127) at 1/1000 dilutionLane 1 : Jurkat cell lysatesLane 2 : MOLT4 cell lysatesLysates/proteins at 10 µg per lane.

Anti-c-Myb antibody [MYB286] - ab190825 from Abcam

Prices $372.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone MYB286

Anti-v-Myb + c-Myb (phospho S12) antibody - ab78892 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded human heart tissue using ab78892 at 1/50 dilution in the absence or presence of the immunising phosphopeptide.

Anti-v-Myb + c-Myb antibody [EP769Y] - ChIP Grade - ab45150 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP769Y
Anti-v-Myb + c-Myb antibody [EP769Y] - ChIP Grade (ab45150) at 1/10000 dilution + Ramos membrane

Anti-v-Myb + c-Myb antibody [EP769Y] - ChIP Grade (Alexa Fluor® 488) - ab197507 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP769Y
Overlay histogram showing MCF7 cells stained with ab197507 (red line). The cells were fixed with 4% formaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab197507, 1/50 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 488 used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control.Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.This antibody gave a positive signal in MCF7 fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-v-Myb + c-Myb antibody [EP769Y] - ChIP Grade (Alexa Fluor® 647) - ab196932 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP769Y
ab196932 staining v-Myb + c-Myb  in MCF7 cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized in 0.1% Triton X-100 for 5 minutes and then blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated with ab196932 at 1/50 dilution (shown in red) and ab195887, Mouse monoclonal [DM1A] to alpha Tubulin (Alexa Fluor® 488, shown in green) at 1/167 dilution, overnight at +4°C. Nuclear DNA was labelled in blue with DAPI.Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-v-Myb + c-Myb antibody [SPM175] - ab17851 from Abcam

Prices $376.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone SPM175
Human seminoma stained with ab17851.

Anti-v-Myb + c-Myb antibody [SPM175], prediluted - ab53921 from Abcam

Host Mouse
Clonality Monoclonal
Clone SPM175
ab53921 (prediluted) staining v-Myb / c-Myb in formalin fixed, paraffin embedded human seminoma tissue by Immunohistochemistry.
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