Fbxo43
| Gene Symbol | Fbxo43 |
|---|---|
| Entrez Gene | 315034 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | F-box protein 43 |
| Other Description | F-box only protein 43|endogenous meiotic inhibitor 2 |
| Swissprots | Q66H04 |
| Accessions | EDM16401 Q66H04 BC082107 AAH82107 XM_006241535 XP_006241597 NM_001012117 NP_001012117 |
| Function | Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (By similarity). {ECO:0000250}. |
| Top Pathways | Oocyte meiosis |
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