Gene Symbol | Fbxo43 |
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Entrez Gene | 315034 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | F-box protein 43 |
Other Description | F-box only protein 43|endogenous meiotic inhibitor 2 |
Swissprots | Q66H04 |
Accessions | EDM16401 Q66H04 BC082107 AAH82107 XM_006241535 XP_006241597 NM_001012117 NP_001012117 |
Function | Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (By similarity). {ECO:0000250}. |
Top Pathways | Oocyte meiosis |
CompoZr® Knockout ZFN Kit - CKOZFN53930 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND53930 from Sigma-Aldrich
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FBXO43 siRNA (Rat) - CRR5506 from Cohesion Biosciences
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FBXO43 - MBS8200600 from MyBioSource
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shRNA set against Rat FBXO43 (NM_001012117.1) - SHH293337 from Creative biogene
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Rat FBXO43 siRNA - orb300355 from Biorbyt
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FBXO43 shRNA Plasmid (Rat) - CHR5506 from Cohesion Biosciences
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