| Gene Symbol |
Fbxo43
|
| Entrez Gene |
315034
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
F-box protein 43
|
| Other Description |
F-box only protein 43|endogenous meiotic inhibitor 2
|
| Swissprots |
Q66H04
|
| Accessions |
EDM16401 Q66H04 BC082107 AAH82107 XM_006241535 XP_006241597 NM_001012117 NP_001012117
|
| Function |
Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (By similarity). {ECO:0000250}.
|
| Top Pathways |
Oocyte meiosis
|