| Gene Symbol | ABCC2 |
|---|---|
| Entrez Gene | 1244 |
| Alt Symbol | ABC30, CMOAT, DJS, MRP2, cMRP |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| Other Description | canalicular multidrug resistance protein|canalicular multispecific organic anion transporter 1|multidrug resistance-associated protein 2 |
| Swissprots | B2RMT8 Q92798 Q92500 Q5T2B1 Q14022 Q99663 Q9UMS2 Q92887 |
| Accessions | AAD47599 CAB45309 CAJ33679 CAS97349 EAW49852 EAW49853 Q92887 BC136419 AAI36420 BM765259 CB120555 U49248 AAB09422 U63970 AAB39892 U66683 X96395 CAA65259 XM_006717630 XP_006717693 XM_006717631 XP_006717694 XM_011539291 XP_011537593 XR_945604 XR_945605 NM_000392 NP_000383 |
| Function | Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter. |
| Subcellular Location | Apical cell membrane {ECO:0000269|PubMed:11093739}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:11093739}. |
| Tissue Specificity | Expressed by polarized cells in liver, kidney and intestine. The highest expression is found in liver. |
| Top Pathways | ABC transporters, Bile secretion |