Gene Symbol | ABCC2 |
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Entrez Gene | 1244 |
Alt Symbol | ABC30, CMOAT, DJS, MRP2, cMRP |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
Other Description | canalicular multidrug resistance protein|canalicular multispecific organic anion transporter 1|multidrug resistance-associated protein 2 |
Swissprots | B2RMT8 Q92798 Q92500 Q5T2B1 Q14022 Q99663 Q9UMS2 Q92887 |
Accessions | AAD47599 CAB45309 CAJ33679 CAS97349 EAW49852 EAW49853 Q92887 BC136419 AAI36420 BM765259 CB120555 U49248 AAB09422 U63970 AAB39892 U66683 X96395 CAA65259 XM_006717630 XP_006717693 XM_006717631 XP_006717694 XM_011539291 XP_011537593 XR_945604 XR_945605 NM_000392 NP_000383 |
Function | Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter. |
Subcellular Location | Apical cell membrane {ECO:0000269|PubMed:11093739}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:11093739}. |
Tissue Specificity | Expressed by polarized cells in liver, kidney and intestine. The highest expression is found in liver. |
Top Pathways | ABC transporters, Bile secretion |
Human MRP2 protein fragment - ab112272 from Abcam
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ABCC2 / MRP2 Antibody Blocking Peptide - LS-E16049 from LifeSpan Bioscience
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Recombinant Human MRP2 Protein - H00001244-Q01 from Novus Biologicals
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Abcc2 Blocking Peptide - 33R-9125 from Fitzgerald
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MRP2 Blocking Peptide - abx062441 from Abbexa
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ABCC2 / CMOAT / MRP2 - H00001244-Q01-10 from Acris Antibodies
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ABCC2 / CMOAT / MRP2 - H00001244-Q01-25 from Acris Antibodies
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Macrophage Inflammatory Protein-1 gamma, MIP-1 gamma (CCL9/CCL10), Mouse, Recombinant - 28-20101 from ARP American Research Products
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ABCC2 fusion protein - Ag18694 from Proteintech Group
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Recombinant Human ABCC2 - ABCC2-2537H from Creative Biomart
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Recombinant Human ABCC2, GST-tagged - ABCC2-9216H from Creative Biomart
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Recombinant Human ABCC2 - ABCC2-515H from Creative Biomart
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mMIP-1g - KJB-381 from Reagent Proteins
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Recombinant ATP Binding Cassette Transporter C2 (ABCC2) - RPD622Hu01 from Uscn Life Science Inc.
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MRP2 Blocking Peptide - CBP1247 from Cohesion Biosciences
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MRP2 Peptide - BS5801P from Bioworld Technology
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Recombinant ATP Binding Cassette Transporter C2 (ABCC2) - RPD622Hu01 from Cloud-clone
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ABCC2 Protein - abx163226 from Abbexa
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MRP2 Recombinant Protein Antigen - NBP1-84434PEP from Novus Biologicals
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MRP2 protein - orb86175 from Biorbyt
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ABCC2 Peptide, Human - M34GP00053H from Creative Peptides
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ABCC2 Recombinant Protein (OPCD01010) - OPCD01010 from Aviva Systems Biology
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Recombinant Human ABCC2 Protein, GST-Tagged - ABCC2-047H from Creative Biomart
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Recombinant Human ABCC2 protein, His-tagged - ABCC2-8117H from Creative Biomart
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