ABCC2

Gene Symbol ABCC2
Entrez Gene 1244
Alt Symbol ABC30, CMOAT, DJS, MRP2, cMRP
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Other Description canalicular multidrug resistance protein|canalicular multispecific organic anion transporter 1|multidrug resistance-associated protein 2
Swissprots B2RMT8 Q92798 Q92500 Q5T2B1 Q14022 Q99663 Q9UMS2 Q92887
Accessions AAD47599 CAB45309 CAJ33679 CAS97349 EAW49852 EAW49853 Q92887 BC136419 AAI36420 BM765259 CB120555 U49248 AAB09422 U63970 AAB39892 U66683 X96395 CAA65259 XM_006717630 XP_006717693 XM_006717631 XP_006717694 XM_011539291 XP_011537593 XR_945604 XR_945605 NM_000392 NP_000383
Function Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:11093739}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:11093739}.
Tissue Specificity Expressed by polarized cells in liver, kidney and intestine. The highest expression is found in liver.
Top Pathways ABC transporters, Bile secretion

MRP2 CRISPR/Cas9 KO Plasmid (h) - sc-400601 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 HDR Plasmid (h) - sc-400601-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 Double Nickase Plasmid (h) - sc-400601-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 Double Nickase Plasmid (h2) - sc-400601-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 CRISPR Activation Plasmid (h) - sc-400601-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 CRISPR Activation Plasmid (h2) - sc-400601-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 Lentiviral Activation Particles (h) - sc-400601-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 Lentiviral Activation Particles (h2) - sc-400601-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP2 siRNA (h) - sc-35963 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRP2 shRNA Plasmid (h) - sc-35963-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRP2 shRNA (h) Lentiviral Particles - sc-35963-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU052041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1169 from Sigma-Aldrich

Category ZFN Kit
Prices $6,000.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00796 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00796

ABCC2 siRNA (Human) - CRH0877 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCC2 - MBS827825 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Abcc2 (NM_000392.3) - SHH229114 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ABCC2(NM_000392.3) - SHG023969 from Creative biogene

Category siRNA
Species Reactivities Human

Human ABCC2 siRNA - orb261379 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCC2 shRNA Plasmid (Human) - CHH0877 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ABCC2 miRNA 3'UTR clone - MiUTR1H-00040 from Creative biogene

Species Reactivities Human
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