CD36

Gene Symbol CD36
Entrez Gene 948
Alt Symbol BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3
Species Human
Gene Type protein-coding
Description CD36 molecule (thrombospondin receptor)
Other Description CD36 antigen (collagen type I receptor, thrombospondin receptor)|GPIIIB|PAS IV|PAS-4 protein|cluster determinant 36|fatty acid translocase|glycoprotein IIIb|leukocyte differentiation antigen CD36|platelet glycoprotein 4|platelet glycoprotein IV|scavenger receptor class B, member 3
Swissprots Q9BQC2 D9IX67 Q9BZN5 D9IX66 D9IX68 Q9BZM8 Q16093 Q9BZN4 D9IX69 Q8TCV7 P16671 Q9BPZ8 Q9BZN3 Q13966
Accessions AAB46390 AAG60624 AAG60625 AAG60626 AAG60627 AAG60628 AAG60629 AAG60630 AAG60631 AAG60632 AAG60633 AAG60634 AAG60635 AAG60636 AAG60637 AAG60638 AAG60639 AAM14636 AHA62517 AIY28314 AIY28315 CAA80504 CAA83662 CBH19823 EAL24191 EAW76996 EAW76997 EAW76998 EAW76999 EAW77000 EAW77001 EAW77002 EAW77003 EAW77004 EAW77005 P16671 AA846141 AK057690 AK096858 BAG53380 AK129899 AK300101 BAH13209 AK312920 BAG35765 AL596924 BC008406 AAH08406 BP258762 BP259746 CR749465 DA566475 DA857400 DC338512 DQ893062 ABM83988 DQ896314 ABM87313 HM217020 ADI80540 HM217021 ADI80541 HM217022 ADI80542 HM217023 ADI80543 HM217024 ADI80544 HM217025 ADI80545 HM217026 ADI80546 L06850 AAA16068 M24795 AAA35534 M98398 AAA58412 M98399 AAA58413 S60719 AAD14932 S60720 AAD14933 S67044 AAB28992 S67532 AAD13993 XM_005250713 XP_005250770 XM_005250714 XP_005250771 XM_005250715 XP_005250772 XM_011516707 XP_011515009 NM_000072 NP_000063 NM_001001547 NP_001001547 NM_001001548 NP_001001548 NM_001127443 NP_001120915 NM_001127444 NP_001120916 NM_001289908 NP_001276837 NM_001289909 NP_001276838 NM_001289911 NP_001276840 NR_110501
Function Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. {ECO:0000269|PubMed:10890433, ECO:0000269|PubMed:12506336, ECO:0000269|PubMed:20037584}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Note=Upon ligand-binding, internalized through dynamin-dependent endocytosis. {ECO:0000269|PubMed:20037584}.
Top Pathways ECM-receptor interaction, Hematopoietic cell lineage, Adipocytokine signaling pathway, PPAR signaling pathway, Phagosome

CD36 (D8L9T) Rabbit mAb - 14347 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D8L9T
Western blot analysis of extracts from various cell lines using CD36 (D8L9T) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower). Expression of CD36 was induced in the THP-1 cell line using TPA #4174 (80 nm, 16hrs).

CD36 (N-15) - sc-5522 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD36 (N-15): sc-5522. Western blot analysis of CD36 expression in platelet extract (A) and human PBL (B) and mouse PBL (C) whole cell lysates.

CD36 (SMφ) - sc-7309 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD36 (SMφ): sc-7309. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.

CD36 (L-17) - sc-5523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD36 (L-17): sc-5523. Western blot analysis of CD36 expression in platelet extract (A) and human PBL (B) and mouse PBL (C) whole cell lysates.

CD36 (1A7) - sc-73643 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

CD36 (H-300) - sc-9154 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD36 (H-300): sc-9154. Western blot analysis of human recombinant CD36 fusion protein.

CD36 (185-1G2) - sc-21772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD36 (185-1G2) FITC: sc-21772 FITC. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-2856.

CD36 (V-19) - sc-7641 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD36 (V-19): sc-7641. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.

CD36 (5K65) - sc-70644 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

CD36 (1.BB.344) - sc-70642 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-CD36 antibody - ab78054 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD36 antibody (ab78054)Lane 1 : Lysate prepared from human platelets at 15 µgLane 2 : Lysate prepared from human platelets at 30 µg

Anti-CD36 antibody - ab137320 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD36 antibody (ab137320) at 1/1000 dilution + K562 whole cell lysate at 30 µg

Anti-CD36 antibody - ab64014 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD36 antibody (ab64014) at 1 µg/mlLane 1 : Human Platelet (Human adult normal cell line) Whole Cell Lysate Lane 2 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 3 : Adipose (Human) Total Protein Lysate - adult normal tissue (ab28980)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD36 antibody - ab105096 from Abcam

Host Goat
Clonality Polyclonal

Anti-CD36 antibody [185-1G2] - ab76521 from Abcam

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 185-1G2
Human peripheral blood cells stained with ab76521 (red line). Human whole blood was processed using a modified protocol based on Chow et al, 2005 (PMID: 16080188). In brief, human whole blood was fixed in 4% formaldehyde (methanol-free) for 10 min at 22°C. Red blood cells were then lyzed by the addition of Triton X-100 (final concentration - 0.1%) for 15 min at 37°C. For experimentation, cells were treated with 50% methanol (-20°C) for 15 min at 4°C. Cells were then incubated with the antibody (ab76521, 0.1μg/1x106 cells) for 30 min at 4°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 4°C. Acquisition of >30,000 total events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-CD36 antibody [5B6B2] - ab202023 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B6B2
Anti-CD36 antibody [5B6B2] (ab202023) at 1/500 dilution + Human CD36 (aa: 30-130) recombinant protein at 1 µg

Anti-CD36 antibody [CB38 (NL07)], prediluted (Phycoerythrin) - ab139369 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone CB38 (NL07)

Anti-CD36 antibody [EPR6573] - ab133625 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6573
Anti-CD36 antibody [EPR6573] (ab133625) at 1/100 dilution (unpurified) + Rat heart tissue lysate at 10 µgSecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-CD36 antibody [FA6-152] - ab17044 from Abcam

Prices $385.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone FA6-152
Overlay histogram showing THP1 cells stained with ab17044 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab17044, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive result in 80% methanol (5 min) fixed THP1 cells used under the same conditions.Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-CD36 antibody [JC63.1] - ab23680 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone JC63.1
Immunofluorescence analysis of 3T3-L1 adipocytes, staining CD36 with ab23680.Cells were fixed with paraformaldehyde, permeabilized with 0.01% saponin and blocked with 1% BSA. Samples were incubated with primary antibody overnight at 4°C.

Anti-CD36 antibody [MF3] - Low endotoxin, Azide free - ab80080 from Abcam

Prices $395.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone MF3
ab80080 at 10µl/106 cells staining CD36 in mouse peripheral blood platelets by Flow Cytometry.

Anti-CD36 antibody [MM0170-7K35] - ab89212 from Abcam

Prices $370.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone MM0170-7K35

Anti-CD36 antibody [SM0] (FITC) - ab30412 from Abcam

Prices $372.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone SM0

Anti-CD36 antibody [SMf] (FITC) - ab82443 from Abcam

Prices $372.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone SMf

Anti-CD36 antibody [SMomega] - ab77145 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone SMomega
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