Ube2c

Gene Symbol Ube2c
Entrez Gene 68612
Alt Symbol 1110015A16Rik, D2Ertd695e
Species Mouse
Gene Type protein-coding
Description ubiquitin-conjugating enzyme E2C
Other Description ubcH10|ubiquitin carrier protein C|ubiquitin-conjugating enzyme E2 C|ubiquitin-protein ligase C
Swissprots Q3TUJ0 Q9D1C1
Accessions EDL06414 Q9D1C1 AK003722 BAB22959 AK136186 BAE22863 AK160740 BAE35981 BC147032 AAI47033 BC147033 AAI47034 BC171983 NM_026785 NP_081061
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit (By similarity). {ECO:0000250}.
Top Pathways Ubiquitin mediated proteolysis

Mouse Ube2c ORF clone - CDCH097342 from Creative Biomart

Species Mouse
Accession NM_026785

Mouse Ube2c ORF clone - CDCH097343 from Creative Biomart

Species Mouse
Accession NM_026785

Mouse UBE2C ORF clone(NM_026785.2) - CDCR008157 from Creative Biomart

Species Mouse
Accession NM_026785.2

Mouse Ube2c ORF Clone(NM_026785.2) - CDCR259273 from Creative Biomart

Species Mouse
Accession NM_026785.2

Mouse Ube2c ORF Clone(NM_026785.2) - CDCR259274 from Creative Biomart

Species Mouse
Accession NM_026785.2

Mouse Ube2c ORF Clone(NM_026785.2) - CDCR259273 from Creative biogene

Species Mouse
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