GOT2

Gene Symbol GOT2
Entrez Gene 2806
Alt Symbol KAT4, KATIV, mitAAT
Species Human
Gene Type protein-coding
Description glutamic-oxaloacetic transaminase 2, mitochondrial
Other Description FABP-1|FABPpm|aspartate aminotransferase 2|aspartate aminotransferase, mitochondrial|aspartate transaminase 2|fatty acid-binding protein|glutamate oxaloacetate transaminase 2|glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)|kynurenine aminotransferase 4|kynurenine aminotransferase IV|kynurenine--oxoglutarate transaminase 4|kynurenine--oxoglutarate transaminase IV|mAspAT|plasma membrane-associated fatty acid-binding protein|transaminase A
Swissprots Q53FL3 Q9BWA3 E7ERW2 B4DJA6 P00505
Accessions EAW82988 EAW82989 P00505 AK098313 BAG53610 AK223271 BAD96991 AK290847 BAF83536 AK295993 BAG58768 AK302249 BAG63601 AK307598 AL516773 BC000525 AAH00525 BI667777 DB485399 DQ891883 ABM82809 DQ895068 ABM85994 M22632 AAA35568 NM_001286220 NP_001273149 NM_002080 NP_002071
Function Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. {ECO:0000269|PubMed:9537447}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:9537447}. Cell membrane {ECO:0000269|PubMed:9537447}. Note=Exposure to alcohol promotes translocation to the cell membrane.
Top Pathways Cysteine and methionine metabolism, Fat digestion and absorption, Alanine, aspartate and glutamate metabolism, 2-Oxocarboxylic acid metabolism, Carbon metabolism

AATM CRISPR/Cas9 KO Plasmid (h) - sc-403969 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM HDR Plasmid (h) - sc-403969-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM Double Nickase Plasmid (h) - sc-403969-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM Double Nickase Plasmid (h2) - sc-403969-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM CRISPR Activation Plasmid (h) - sc-403969-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM CRISPR Activation Plasmid (h2) - sc-403969-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM Lentiviral Activation Particles (h) - sc-403969-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM Lentiviral Activation Particles (h2) - sc-403969-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AATM siRNA (h) - sc-60052 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AATM shRNA Plasmid (h) - sc-60052-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AATM shRNA (h) Lentiviral Particles - sc-60052-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GOT2 RNAi - H00002806-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU015001 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9493 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9493 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12476 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12476

GOT2 siRNA (Human) - CRH1876 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GOT2 - MBS8210200 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GOT2 (NM_002080.2) - SHH305506 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GOT2(NM_002080.2) - SHH094871 from Creative biogene

Category siRNA
Species Reactivities Human

Human GOT2 siRNA - orb262378 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GOT2 shRNA Plasmid (Human) - CHH1876 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GOT2 miRNA 3'UTR clone - MiUTR1H-04147 from Creative biogene

Species Reactivities Human
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