UGT2B28

Gene Symbol UGT2B28
Entrez Gene 54490
Alt Symbol -
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 2 family, polypeptide B28
Other Description UDP glycosyltransferase 2 family, polypeptide B28|UDP-glucuronosyltransferase 2B28|UDPGT 2B28
Swissprots Q9BY62 Q9BY64 B5BUM0 Q9BY63
Accessions EAX05588 EAX05589 EAX05590 Q9BY64 AB451456 BAG70270 AF177272 AAK31807 AF177273 AAK31808 AF177274 AAK31809 BC156172 AAI56173 BC157011 AAI57012 XM_011532036 XP_011530338 NM_001207004 NP_001193933 NM_053039 NP_444267
Function UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta- diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active. {ECO:0000269|PubMed:11300766}.
Subcellular Location Microsome membrane {ECO:0000269|PubMed:11300766}; Single-pass membrane protein {ECO:0000269|PubMed:11300766}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:11300766}; Single-pass membrane protein {ECO:0000269|PubMed:11300766}.
Tissue Specificity Expressed in the liver, breast and kidney. {ECO:0000269|PubMed:11300766}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

Anti-UGT antibody [7H2AF11] - ab129729 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7H2AF11
Overlay histogram showing HepG2 cells stained with ab129729 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab129729, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was an anti-mouse Alexa Fluor® 488 (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-UGT2B28 antibody - ab156131 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-UGT2B28 antibody (ab156131) at 1/100 dilution + ZR-75-1 cell line lysates at 35 µg

Anti-UGT2B28 Antibody (aa218-246, AP) - LS-C273015 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGT2B28 Antibody (aa218-246, Biotin) - LS-C273018 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGT2B28 Antibody (aa218-246, FITC) - LS-C273019 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGT2B28 Antibody (aa218-246, APC) - LS-C273017 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGT2B28 Antibody (aa218-246, PE) - LS-C273020 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGT2B28 Antibody (aa218-246) - LS-C326175 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGT2B28 Antibody (aa218-246, Azide-free, HRP) - LS-C273021 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGT2B28 Antibody (aa218-246) - LS-C157017 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UGT2B28 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The UGT2B28 antibody detected the UGT2B28 protein (arrow).

ANTI-UGT2B28 (CENTER) antibody produced in rabbit - SAB1305950 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UGT2B28 (Center): <B>Cat. No. SAB1305950</B>: UGT2B28 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35 μg/lane).

UGT2B28-AntibodyCenter - AP19881c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
UGT2B28 Antibody (Center) (Cat. #AP19881c) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the UGT2B28 antibody detected the UGT2B28 protein (arrow).

UGT2B28Antibody - middle region (OAAB15342) - OAAB15342 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

UGT2B28 Antibody - abx031269 from Abbexa

Host Rabbit
Clonality Polyclonal

UGT2B28 antibody - H00054490-B01P from Acris Antibodies

Prices $360.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

Rabbit Anti-Human UGT2B28(Center) - 102-14467 from RayBiotech

Host Rabbit
UGT2B28 Antibody (Center) (Cat# 102-14467) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the UGT2B28 antibody detected the UGT2B28 protein (arrow).

UGT2B28 antibody (Center) - STJ47794 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB41660

Anti-UGT2B28 (aa 218-246) polyclonal antibody - DPABH-05488 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

UGT2B28, Polyclonal Antibody - MBS9208177 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

UGT2B28 Antibody - 60-762 from ProSci

Prices $375.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
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