| Gene Symbol |
GP1BB
|
| Entrez Gene |
2812
|
| Alt Symbol |
BDPLT1, BS, CD42C, GPIBB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycoprotein Ib (platelet), beta polypeptide
|
| Other Description |
GP-Ib beta|antigen CD42b-beta|nuclear localization signal deleted in velocardiofacial syndrome|platelet glycoprotein Ib beta chain
|
| Swissprots |
P13224 Q14422 Q8NG40
|
| Accessions |
AAC39781 ADZ28540 ADZ28541 ADZ28542 BAC00777 CBX54455 CDI44162 P13224 BC160146 AAI60146 J03259 AAA52594 NM_000407 NP_000398
|
| Function |
Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Expressed in heart and brain. {ECO:0000269|PubMed:8200976}.
|
| Top Pathways |
ECM-receptor interaction, Hematopoietic cell lineage
|