Gene Symbol | GP1BB |
---|---|
Entrez Gene | 2812 |
Alt Symbol | BDPLT1, BS, CD42C, GPIBB |
Species | Human |
Gene Type | protein-coding |
Description | glycoprotein Ib (platelet), beta polypeptide |
Other Description | GP-Ib beta|antigen CD42b-beta|nuclear localization signal deleted in velocardiofacial syndrome|platelet glycoprotein Ib beta chain |
Swissprots | P13224 Q14422 Q8NG40 |
Accessions | AAC39781 ADZ28540 ADZ28541 ADZ28542 BAC00777 CBX54455 CDI44162 P13224 BC160146 AAI60146 J03259 AAA52594 NM_000407 NP_000398 |
Function | Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in heart and brain. {ECO:0000269|PubMed:8200976}. |
Top Pathways | ECM-receptor interaction, Hematopoietic cell lineage |