Gene Symbol | GP1BB |
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Entrez Gene | 2812 |
Alt Symbol | BDPLT1, BS, CD42C, GPIBB |
Species | Human |
Gene Type | protein-coding |
Description | glycoprotein Ib (platelet), beta polypeptide |
Other Description | GP-Ib beta|antigen CD42b-beta|nuclear localization signal deleted in velocardiofacial syndrome|platelet glycoprotein Ib beta chain |
Swissprots | P13224 Q14422 Q8NG40 |
Accessions | AAC39781 ADZ28540 ADZ28541 ADZ28542 BAC00777 CBX54455 CDI44162 P13224 BC160146 AAI60146 J03259 AAA52594 NM_000407 NP_000398 |
Function | Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in heart and brain. {ECO:0000269|PubMed:8200976}. |
Top Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
CD42c CRISPR/Cas9 KO Plasmid (h) - sc-403712 from Santa Cruz Biotechnology
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CD42c HDR Plasmid (h) - sc-403712-HDR from Santa Cruz Biotechnology
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CD42c Double Nickase Plasmid (h) - sc-403712-NIC from Santa Cruz Biotechnology
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CD42c Double Nickase Plasmid (h2) - sc-403712-NIC-2 from Santa Cruz Biotechnology
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CD42c CRISPR Activation Plasmid (h) - sc-403712-ACT from Santa Cruz Biotechnology
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CD42c CRISPR Activation Plasmid (h2) - sc-403712-ACT-2 from Santa Cruz Biotechnology
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CD42c Lentiviral Activation Particles (h) - sc-403712-LAC from Santa Cruz Biotechnology
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CD42c Lentiviral Activation Particles (h2) - sc-403712-LAC-2 from Santa Cruz Biotechnology
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CD42c siRNA (h) - sc-42790 from Santa Cruz Biotechnology
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CD42c shRNA Plasmid (h) - sc-42790-SH from Santa Cruz Biotechnology
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CD42c shRNA (h) Lentiviral Particles - sc-42790-V from Santa Cruz Biotechnology
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GP1BB RNAi - H00002812-R02 from Novus Biologicals
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MISSION® esiRNA - EHU117741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9495 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9495 from Sigma-Aldrich
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GP1BB siRNA (Human) - CRH1879 from Cohesion Biosciences
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GP1BB - MBS8237235 from MyBioSource
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shRNA set against Human GP1BB (NM_000407.4) - SHH305530 from Creative biogene
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shRNA set against Human GP1BB(NM_000407.4) - SHH094961 from Creative biogene
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Human GP1BB siRNA - orb262381 from Biorbyt
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GP1BB shRNA Plasmid (Human) - CHH1879 from Cohesion Biosciences
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GP1BB miRNA 3'UTR clone - MiUTR1H-04148 from Creative biogene
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