Gene Symbol | SLC2A4 |
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Entrez Gene | 6517 |
Alt Symbol | GLUT4 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 2 (facilitated glucose transporter), member 4 |
Other Description | GLUT-4|glucose transporter type 4, insulin-responsive|insulin-responsive glucose transporter type 4|solute carrier family 2, facilitated glucose transporter member 4 |
Swissprots | Q05BQ3 P14672 Q14CX2 |
Accessions | AAA52569 CAA41399 EAW90226 EAW90227 P14672 AK300899 BAG62537 AK313372 BAG36171 AL521328 BC034387 AAH34387 BC069615 AAH69615 BC069621 AAH69621 BC113592 AAI13593 BC126164 AAI26165 BQ775137 CF594356 HQ258267 ADR83021 M20747 AAA59189 NM_001042 NP_001033 |
Function | Insulin-regulated facilitative glucose transporter. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endomembrane system {ECO:0000269|PubMed:8300557}; Multi-pass membrane protein {ECO:0000269|PubMed:8300557}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:8300557}. Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration. |
Tissue Specificity | Skeletal and cardiac muscles; brown and white fat. |
Top Pathways | Insulin signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, AMPK signaling pathway |
Glut4 (1F8) Mouse mAb - 2213 from Cell Signaling Technology
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Glut4 Antibody - 9001 from Cell Signaling Technology
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Glut4 Antibody - 2299 from Cell Signaling Technology
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Glut4 (C-20) - sc-1608 from Santa Cruz Biotechnology
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Glut4 (IF8) - sc-53566 from Santa Cruz Biotechnology
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Glut4 (H-61) - sc-7938 from Santa Cruz Biotechnology
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Glut4 (N-20) - sc-1606 from Santa Cruz Biotechnology
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p-Glut4 (Ser 488) - sc-17558 from Santa Cruz Biotechnology
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Anti-Glucose Transporter GLUT4 (phospho S488) antibody [EPR930(2)] - ab188317 from Abcam
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Anti-Glucose Transporter GLUT4 antibody - ab654 from Abcam
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Anti-Glucose Transporter GLUT4 antibody - ab41529 from Abcam
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Anti-Glucose Transporter GLUT4 antibody - ab133434 from Abcam
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Anti-Glucose Transporter GLUT4 antibody [1F8] - ab35826 from Abcam
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Anti-Glucose Transporter GLUT4 antibody [3G10A3] - ab166704 from Abcam
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Anti-SLC2A4 / GLUT-4 Antibody (aa333-509) - LS-C343974 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (C-Terminus) - LS-C15411 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody - LS-C15409 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (C-Terminus) - LS-C15410 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (N-Terminus) - LS-C41923 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (C-Terminus) - LS-C121888 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (C-Terminus) - LS-C121889 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody - LS-C123618 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (aa498-509) - LS-C127595 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (aa480-530, DY488) - LS-C143213 from LifeSpan Bioscience
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Anti-SLC2A4 / GLUT-4 Antibody (N-Terminus) - LS-C127596 from LifeSpan Bioscience
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