Gene Symbol | UFSP2 |
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Entrez Gene | 55325 |
Alt Symbol | C4orf20 |
Species | Human |
Gene Type | protein-coding |
Description | UFM1-specific peptidase 2 |
Other Description | ufm1-specific protease 2 |
Swissprots | Q9NUQ7 Q6IA77 Q96FS3 |
Accessions | EAX04645 EAX04646 Q9NUQ7 AK002062 BAA92064 AK091635 BAG52396 BC010493 AAH10493 BF735169 BP264462 CA432183 CR457278 CAG33559 DA537391 XM_011532090 XP_011530392 NM_018359 NP_060829 NR_028085 |
Function | Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation. {ECO:0000269|PubMed:25219498}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Nucleus {ECO:0000250}. |
UFSP2 CRISPR/Cas9 KO Plasmid (h) - sc-408911 from Santa Cruz Biotechnology
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UFSP2 HDR Plasmid (h) - sc-408911-HDR from Santa Cruz Biotechnology
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UFSP2 Double Nickase Plasmid (h) - sc-408911-NIC from Santa Cruz Biotechnology
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UFSP2 Double Nickase Plasmid (h2) - sc-408911-NIC-2 from Santa Cruz Biotechnology
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UFSP2 CRISPR Activation Plasmid (h) - sc-408911-ACT from Santa Cruz Biotechnology
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UFSP2 CRISPR Activation Plasmid (h2) - sc-408911-ACT-2 from Santa Cruz Biotechnology
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UFSP2 Lentiviral Activation Particles (h) - sc-408911-LAC from Santa Cruz Biotechnology
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UFSP2 Lentiviral Activation Particles (h2) - sc-408911-LAC-2 from Santa Cruz Biotechnology
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UFSP2 siRNA (h) - sc-89115 from Santa Cruz Biotechnology
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UFSP2 shRNA Plasmid (h) - sc-89115-SH from Santa Cruz Biotechnology
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UFSP2 shRNA (h) Lentiviral Particles - sc-89115-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22450 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22450 from Sigma-Aldrich
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UFSP2 siRNA (Human) - CRJ0657 from Cohesion Biosciences
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UFSP2 - MBS8228201 from MyBioSource
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shRNA set against Human UFSP2 (NM_018359.3) - SHH439968 from Creative biogene
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UFSP2 shRNA Plasmid (Human) - CHJ0657 from Cohesion Biosciences
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UFSP2 miRNA 3'UTR clone - MiUTR3H-11927 from Creative biogene
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