PCDH8

Gene Symbol	PCDH8
Entrez Gene	5100
Alt Symbol	ARCADLIN, PAPC
Species	Human
Gene Type	protein-coding
Description	protocadherin 8
Other Description	protocadherin-8
Swissprots	Q5TAN1 B4DMV7 Q5TAN2 O95206 Q96SF1 Q8IYE9
Accessions	EAW52049 EAW52050 EAW52051 O95206 AF061573 AAC70009 AK293747 BAG57169 AK297652 BAG60019 AY013873 AAK21986 BC036025 AAH36025 DQ893339 ABM84265 NM_002590 NP_002581 NM_032949 NP_116567
Function	Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane. Note=Also expressed in neuronal cell bodies. Localized to excitatory, but not with inhibitory, synapses. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PCDH8 CRISPR/Cas9 KO Plasmid (h) - sc-405324 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 HDR Plasmid (h) - sc-405324-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 Double Nickase Plasmid (h) - sc-405324-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 Double Nickase Plasmid (h2) - sc-405324-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 CRISPR Activation Plasmid (h) - sc-405324-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 CRISPR Activation Plasmid (h2) - sc-405324-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 Lentiviral Activation Particles (h) - sc-405324-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 Lentiviral Activation Particles (h2) - sc-405324-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PCDH8 siRNA (h) - sc-76085 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PCDH8 shRNA Plasmid (h) - sc-76085-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PCDH8 shRNA (h) Lentiviral Particles - sc-76085-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Protocadherin-8 RNAi - H00005100-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Protocadherin-8 RNAi - H00005100-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Protocadherin-8 RNAi - H00005100-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16409 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16409 from Sigma-Aldrich Category ZFN Kit

MISSION® 3′UTR Lenti GoClone™ - HUTR04188 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04188

PCDH8 siRNA (Human) - CRH3394 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PCDH8 (NM_002590.3) - SHH371516 from Creative biogene Category siRNA Species Reactivities Human

Human PCDH8 siRNA - orb263896 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PCDH8 shRNA Plasmid (Human) - CHH3394 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PCDH8 miRNA 3'UTR clone - MiUTR3H-06080 from Creative biogene Species Reactivities Human

PCDH8 miRNA 3'UTR clone - MiUTR3H-06081 from Creative biogene Species Reactivities Human

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