PCDH8

Gene Symbol PCDH8
Entrez Gene 5100
Alt Symbol ARCADLIN, PAPC
Species Human
Gene Type protein-coding
Description protocadherin 8
Other Description protocadherin-8
Swissprots Q5TAN1 B4DMV7 Q5TAN2 O95206 Q96SF1 Q8IYE9
Accessions EAW52049 EAW52050 EAW52051 O95206 AF061573 AAC70009 AK293747 BAG57169 AK297652 BAG60019 AY013873 AAK21986 BC036025 AAH36025 DQ893339 ABM84265 NM_002590 NP_002581 NM_032949 NP_116567
Function Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane. Note=Also expressed in neuronal cell bodies. Localized to excitatory, but not with inhibitory, synapses. {ECO:0000250}.

PCDH8 (D-7) - sc-377348 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCDH8 (D-7): sc-377348. Western blot analysis of PCDH8 expression in non-transfected: sc-117752 (A) and human PCDH8 transfected: sc-174033 (B) 293T whole cell lysates.

PCDH8 (H-149) - sc-292781 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PCDH8 (H-149): sc-292781. Western blot analysis of PCDH8 expression in non-transfected: sc-117752 (A) and human PCDH8 transfected: sc-174033 (B) 293T whole cell lysates.

PCDH8 (N-15) - sc-84562 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

PCDH8 (JK-19) - sc-81817 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PCDH8 (JK-19): sc-81817. Western blot analysis of PCDH8 expression in COLO 320 HSR whole cell lysate.

Anti-PCDH8 antibody - ab55507 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
PCDH8 antibody (ab55507) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.

Anti-PCDH8 antibody - ab85561 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PCDH8 antibody (ab85561) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PCDH8 antibody - ab85747 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PCDH8 antibody (ab85747) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PCDH8 Antibody (clone 6A8) - LS-C133366 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A8
Western blot of PCDH8 expression in transfected 293T cell line by PCDH8 monoclonal antibody (M01), clone 6A8.

Anti-PCDH8 Antibody (aa883-899) - LS-C3303 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCDH8 Antibody (aa32-121, Azide-free) - LS-C328393 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Protocadherin-8 Antibody - AF5434 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of HT‑29 human colon adenocarcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Human Protocadherin‑8 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5434) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for Protocadherin‑8 at approximately 115 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Protocadherin-8 Antibody (6A8) - H00005100-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6A8
Western Blot: Protocadherin-8 Antibody (6A8) [H00005100-M01] - PCDH8 monoclonal antibody (M01), clone 6A8 Analysis of PCDH8 expression in COLO 320 HSR.

Protocadherin-8 Antibody (562615) - MAB5434 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 562615
Protocadherin‑8 was detected in immersion fixed MCF‑7 human breast cancer cell line using Human Protocadherin-8 Monoclonal Antibody (Catalog # MAB5434) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces and cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Protocadherin-8 Antibody - NBP1-59272 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCDH8 Antibody [NBP1-59272] - 721_B cell lysate, concentration 0.2-1 ug/ml.

Protocadherin-8 Antibody - NBP1-59228 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCDH8 Antibody [NBP1-59228] - Titration: 0.2-1 ug/ml, Positive Control: Human Liver.

Protocadherin-8 Antibody - NBP1-88850 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Protocadherin-8 Antibody [NBP1-88850] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

Protocadherin-8 Antibody - H00005100-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Protocadherin-8 Antibody [H00005100-B01P] - Analysis of PCDH8 expression in transfected 293T cell line by PCDH8 polyclonal antibody. Lane 1: PCDH8 transfected lysate(117.7 KDa). Lane 2: Non-transfected lysate.

Protocadherin-8 Antibody (1C5) - H00005100-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C5
Sandwich ELISA: Protocadherin-8 Antibody (1C5) [H00005100-M02] - Detection limit for recombinant GST tagged PCDH8 is 0.1 ng/ml as a capture antibody.

Protocadherin-8 Antibody - H00005100-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PCDH8 Polyclonal Antibody - bs-11114R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1: HepG2 lysates probed with Anti PCDH8 Polyclonal Antibody, Unconjugated (bs-11114R) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:5000 for 90 min at 37˚C.

PCDH8 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11114R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCDH8 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11114R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCDH8 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11114R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCDH8 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11114R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCDH8 Polyclonal Antibody, Cy3 Conjugated - bs-11114R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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