Gene Symbol | NKRF |
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Entrez Gene | 55922 |
Alt Symbol | ITBA4, NRF |
Species | Human |
Gene Type | protein-coding |
Description | NFKB repressing factor |
Other Description | NF-kappa-B-repressing factor|transcription factor NRF |
Swissprots | O15226 Q4VC41 G3V1N1 Q9UJ91 |
Accessions | EAW89859 EAW89860 O15226 AA845622 AJ011812 CAB56459 AL539002 AY208891 AAP43025 BC040379 AAH40379 BC047878 AAH47878 BC068514 AAH68514 EF158333 ABM16955 EF165090 ABM55375 EF165091 ABM55376 EF165092 ABM55377 EF165093 ABM55378 EF165094 ABM55379 EF165095 ABM55380 EF216688 ABN11234 EF216689 ABN11235 Y07707 CAA68976 XM_011531365 XP_011529667 NM_001173487 NP_001166958 NM_001173488 NP_001166959 NM_017544 NP_060014 |
Function | Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. {ECO:0000269|PubMed:12381793}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
Tissue Specificity | Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney. |
NKRF (E-12) - sc-365568 from Santa Cruz Biotechnology
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NKRF (H-300) - sc-134788 from Santa Cruz Biotechnology
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NKRF (N-17) - sc-54134 from Santa Cruz Biotechnology
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NKRF (E-16) - sc-54133 from Santa Cruz Biotechnology
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NKRF (C-19) - sc-54132 from Santa Cruz Biotechnology
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Anti-NKRF antibody [2639C1a] - ab71963 from Abcam
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Anti-NKRF / NRF Antibody (C-Terminus) IHC-plus⢠- LS-B3529 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody - LS-C73459 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (clone 2639C1a) - LS-C184678 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (N-Terminus) - LS-C30923 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (aa61-110) - LS-C110098 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (aa36-85) - LS-C110099 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (clone 2639C1a) - LS-C342709 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (aa1-296, clone 4C2) - LS-C339839 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (aa50-100) - LS-C290661 from LifeSpan Bioscience
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Anti-NKRF / NRF Antibody (aa205-233) - LS-C97793 from LifeSpan Bioscience
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NKRF Antibody - NBP2-15041 from Novus Biologicals
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NKRF Antibody - H00055922-B01 from Novus Biologicals
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NKRF Antibody - H00055922-B01P from Novus Biologicals
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NKRF Antibody (1F6) - H00055922-M06 from Novus Biologicals
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Anti-NKRF (ab2) antibody produced in rabbit - SAB2101596 from Sigma-Aldrich
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Monoclonal Anti-NKRF, (C-terminal) antibody produced in mouse - SAB1402602 from Sigma-Aldrich
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Anti-NKRF (ab3) antibody produced in rabbit - SAB2101597 from Sigma-Aldrich
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Anti-NKRF (ab1) antibody produced in rabbit - SAB2101595 from Sigma-Aldrich
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Anti-NKRF antibody produced in rabbit - AV39289 from Sigma-Aldrich
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