OLIG2

Gene Symbol	OLIG2
Entrez Gene	10215
Alt Symbol	BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Species	Human
Gene Type	protein-coding
Description	oligodendrocyte lineage transcription factor 2
Other Description	basic domain, helix-loop-helix protein, class B, 1|class B basic helix-loop-helix protein 1|class E basic helix-loop-helix protein 19|human protein kinase C-binding protein RACK17|oligodendrocyte transcription factor 2|oligodendrocyte-specific bHLH transcription factor 2|protein kinase C-binding protein 2
Swissprots	Q05BP9 Q49AL3 Q86X04 B3KRF3 Q9NZ14 Q13516
Accessions	EAX09851 Q13516 AF221520 AAF61215 AK091462 BAG52365 AU130620 BC034681 AAH34681 BC036245 AAH36245 BC036275 BC047511 AAH47511 DA500051 R42179 U48250 AAC72247 XM_005260908 XP_005260965 NM_005806 NP_005797
Function	Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. Cytoplasm {ECO:0000250}. Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. {ECO:0000250}.
Tissue Specificity	Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. {ECO:0000269|PubMed:11498220, ECO:0000269|PubMed:11526205}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Active human Olig2 full length protein - ab169905 from Abcam Category Protein Prices $588.00 Sizes 50 µg Source E. coli Species Human

Human Olig2 full length protein - ab112389 from Abcam Category Protein Source Wheat germ Species Human

Human Olig2 peptide - ab111666 from Abcam Category Peptide Species Human

OLIG2 Antibody Blocking Peptide - LS-E6099 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OLIG2 Antibody Blocking Peptide - LS-E11520 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OLIG2 Antibody Blocking Peptide - LS-E11001 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Olig2 Protein - H00010215-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

OLIG2-Antibody-Center-Blocking-Peptide - BP18701c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

OLIG2 - H00010215-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

OLIG2 - H00010215-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

OLIG2 Peptide - 7743P from ProSci Category Peptide Species Human

OLIG2 fusion protein - Ag18838 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

OLIG2 fusion protein - Ag22642 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

OLIG2 fusion protein - Ag5089 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human OLIG2, GST-tagged - OLIG2-28318TH from Creative Biomart Category Protein Source wheat germ Species Human

Recombinant Human OLIG2, GST-tagged - OLIG2-38H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) - RPC690Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

p-OLIG2 (S147) Peptide - AP0734P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

OLIG2 (S147) Peptide - AP0735P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) - RPC690Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant human Oligodendrocyte transcription factor 2 - CSB-EP623814HU from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Oligodendrocyte transcription factor 2(OLIG2) - CSB-YP623814HU CSB-EP623814HU CSB-BP623814HU CSB-MP623814HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

OLIG2 (11-78) - sc-4982 from Santa Cruz Biotechnology Category Protein Prices $167.00 Sizes 50 µg Species Human

OLIG2 - TP308209 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human Oligodendrocyte transcription factor 2 (OLIG2) - CSB-MP623814HU from Cusabio Category Protein Source Mammalian cell Species Human

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