SENP1

Gene Symbol SENP1
Entrez Gene 29843
Alt Symbol SuPr-2
Species Human
Gene Type protein-coding
Description SUMO1/sentrin specific peptidase 1
Other Description SUMO1/sentrin specific protease 1|sentrin-specific protease 1|sentrin/SUMO-specific protease SENP1
Swissprots Q86XC8 A8K7P5 Q9P0U3
Accessions EAW57971 EAW57972 Q9P0U3 AF149770 AAF31171 AK292060 BAF84749 AK312874 AL582855 BC045639 AAH45639 BI560893 BX537920 CAD97903 BX640784 CAE45874 XM_006719361 XP_006719424 XM_006719362 XP_006719425 XM_011538244 XP_011536546 XM_011538245 XP_011536547 NM_001267594 NP_001254523 NM_001267595 NP_001254524 NR_051991 NR_051992 NM_014554
Function Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. {ECO:0000269|PubMed:10652325, ECO:0000269|PubMed:15199155, ECO:0000269|PubMed:16253240, ECO:0000269|PubMed:16553580, ECO:0000269|PubMed:21829689, ECO:0000269|PubMed:21965678, ECO:0000269|PubMed:23160374}.
Subcellular Location Nucleus. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Tissue Specificity Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine. {ECO:0000269|PubMed:15487983}.

SENP1 CRISPR/Cas9 KO Plasmid (h) - sc-417768 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 HDR Plasmid (h) - sc-417768-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 Double Nickase Plasmid (h) - sc-417768-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 Double Nickase Plasmid (h2) - sc-417768-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 CRISPR Activation Plasmid (h) - sc-417768-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 CRISPR Activation Plasmid (h2) - sc-417768-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 Lentiviral Activation Particles (h) - sc-417768-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 Lentiviral Activation Particles (h2) - sc-417768-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP1 siRNA (h) - sc-44449 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SENP1 shRNA Plasmid (h) - sc-44449-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SENP1 shRNA (h) Lentiviral Particles - sc-44449-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU160431 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19085 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19085 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SENP1 siRNA (Human) - CRH9238 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SENP1 - MBS8238816 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human SENP1 siRNA - orb269740 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SENP1 shRNA Plasmid (Human) - CHH9238 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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