DDX39B

Gene Symbol	DDX39B
Entrez Gene	7919
Alt Symbol	BAT1, D6S81E, UAP56
Species	Human
Gene Type	protein-coding
Description	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
Other Description	56 kDa U2AF65-associated protein|ATP-dependent RNA helicase p47|HLA-B-associated transcript 1 protein|nuclear RNA helicase (DEAD family)|spliceosome RNA helicase BAT1|spliceosome RNA helicase DDX39B
Swissprots	Q5STU4 Q5STB8 Q5STU5 O43496 Q2L6F9 Q13838 Q5RJ66 Q5STB4 B0S8C0 Q5ST94 Q71V76 Q0EFA1 Q5STB7 Q5RJ64 Q53GL9 Q5STB5 Q5STU8 Q5STU6
Accessions	AAB94615 AAC63046 BAB63306 BAC54953 BAE78637 BAF31287 CAA75074 EAX03404 EAX03406 EAX03407 EAX03408 EAX03409 EAX03410 EAX03411 EAX03413 Q13838 AB209217 BAD92454 AK127767 AK222912 BAD96632 AK294939 BAG58016 AK295634 BAG58508 AK295854 BAG58660 AK298194 BAG60464 AK316469 BAH14840 BC000361 AAH00361 BC013006 AAH13006 BM993499 BT009909 AAP88911 BU628632 DA048099 DA272922 DQ891881 ABM82807 DQ895067 ABM85993 Z37166 CAA85523 NM_004640 NP_004631 NM_080598 NP_542165 NR_037852
Function	Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. May undergo several rounds of ATP hydrolysis during assembly of TREX to drive subsequent loading of components such as ALYREF/THOC and CHTOP onto mRNA. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Also associates with pre-mRNA independent of ALYREF/THOC4 and the THO complex. Involved in the nuclear export of intronless mRNA; the ATP
Subcellular Location	Nucleus. Nucleus speckle. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1. TREX complex assembly seems to occur in regions surrounding nuclear speckles known as perispeckles.
Top Pathways	Spliceosome, RNA transport, mRNA surveillance pathway, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UAP56 full length protein - ab99297 from Abcam Category Protein Source E. coli Species Human

Human UAP56 peptide - ab48225 from Abcam Category Peptide

DDX39B / UAP56 Antibody Blocking Peptide - LS-E13022 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DDX39B / UAP56 Antibody Blocking Peptide - LS-E13021 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UAP56 Recombinant Protein - H00007919-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

UAP56 Partial Recombinant Protein - H00007919-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human UAP56 Protein - NBP1-48590 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 50 µg, 250 µg Source E. coli Species Human

BAT1-Antibody-C-term-Blocking-Peptide - BP8740b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Spliceosome RNA helicase DDX39B (OPCA00324) - OPCA00324 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

BAT1 Protein (OPPA02559) - OPPA02559 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human BAT1 protein - orb167952 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human DDX39B protein - orb245025 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

BAT1 Blocking Peptide - 33R-5641 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BAT1 Blocking Peptide - 33R-10073 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BAT1 protein (His tag) - 80R-1480 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg Source E.coli

BAT1 / UAP56 (1-428, His-tag) - AR09656PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

BAT1 / UAP56 (1-428, His-tag) - AR09656PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

BAT1 / UAP56 - H00007919-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

BAT1 / UAP56 - H00007919-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BAT1 / UAP56 - H00007919-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BAT1, 1-428aa, Human, His tag, E.coli - 01-BAT-1 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

BAT1 fusion protein - ag6612 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

BAT1 fusion protein - Ag6512 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

BAT1 Human - ENPS-570 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human HLA-B Associated Transcript 1 - BP000695-ENZ-563 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

Search more