DDX39B

Gene Symbol DDX39B
Entrez Gene 7919
Alt Symbol BAT1, D6S81E, UAP56
Species Human
Gene Type protein-coding
Description DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
Other Description 56 kDa U2AF65-associated protein|ATP-dependent RNA helicase p47|HLA-B-associated transcript 1 protein|nuclear RNA helicase (DEAD family)|spliceosome RNA helicase BAT1|spliceosome RNA helicase DDX39B
Swissprots Q5STU4 Q5STB8 Q5STU5 O43496 Q2L6F9 Q13838 Q5RJ66 Q5STB4 B0S8C0 Q5ST94 Q71V76 Q0EFA1 Q5STB7 Q5RJ64 Q53GL9 Q5STB5 Q5STU8 Q5STU6
Accessions AAB94615 AAC63046 BAB63306 BAC54953 BAE78637 BAF31287 CAA75074 EAX03404 EAX03406 EAX03407 EAX03408 EAX03409 EAX03410 EAX03411 EAX03413 Q13838 AB209217 BAD92454 AK127767 AK222912 BAD96632 AK294939 BAG58016 AK295634 BAG58508 AK295854 BAG58660 AK298194 BAG60464 AK316469 BAH14840 BC000361 AAH00361 BC013006 AAH13006 BM993499 BT009909 AAP88911 BU628632 DA048099 DA272922 DQ891881 ABM82807 DQ895067 ABM85993 Z37166 CAA85523 NM_004640 NP_004631 NM_080598 NP_542165 NR_037852
Function Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. May undergo several rounds of ATP hydrolysis during assembly of TREX to drive subsequent loading of components such as ALYREF/THOC and CHTOP onto mRNA. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Also associates with pre-mRNA independent of ALYREF/THOC4 and the THO complex. Involved in the nuclear export of intronless mRNA; the ATP
Subcellular Location Nucleus. Nucleus speckle. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1. TREX complex assembly seems to occur in regions surrounding nuclear speckles known as perispeckles.
Top Pathways Spliceosome, RNA transport, mRNA surveillance pathway, Influenza A

BAT1/DDX39 (H-6) - sc-271395 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAT1/DDX39 (H-6): sc-271395. Western blot analysis of BAT1 expression in non-transfected 293T: sc-117752 (A), human BAT1 transfected 293T: sc-172041 (B) and HeLa (C) whole cell lysates.

BAT1/DDX39 (F-16) - sc-55072 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BAT1/DDX39 (H-198) - sc-68342 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BAT1/DDX39 (H-198): sc-68342. Western blot analysis of DDX39 expression in non-transfected: sc-117752 (A) and human DDX39 transfected: sc-113568 (B) 293T whole cell lysates.

BAT1/DDX39 (G-15) - sc-55073 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BAT1/DDX39 (K-15) - sc-55074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-UAP56 antibody [2060C10a] - ab50986 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2060C10a
Anti-UAP56 antibody [2060C10a] (ab50986) + immunizing peptide

Anti-UAP56 antibody [EPR13144] - ab181059 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13144
All lanes : Anti-UAP56 antibody [EPR13144] (ab181059) at 1/10000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : Jurkat cell lysateLane 4 : 293 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-UAP56 antibody [EPR13144-62] - ab181061 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13144-62
All lanes : Anti-UAP56 antibody [EPR13144-62] (ab181061) at 1/20000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : Jurkat cell lysateLane 4 : 293 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-DDX39B / UAP56 Antibody (clone 2060C10a) - LS-C342378 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2060C10a
Western blot analysis of immunized recombinant protein, using anti-BAT1 monoclonal antibody.

Anti-DDX39B / UAP56 Antibody (clone 2E4) - LS-C172345 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E4
Anti-BAT1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BAT1.

Anti-DDX39B / UAP56 Antibody (clone 2C5) - LS-C115216 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C5
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-BAT1 mouse monoclonal antibody. (Dilution 1:50).

Anti-DDX39B / UAP56 Antibody (C-Terminus) IHC-plus™ - LS-B1512 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DDX39B / UAP56 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1512 concentration 5 ug/ml.

Anti-DDX39B / UAP56 Antibody (aa351-380) - LS-C156747 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human kidney reacted with BAT1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-DDX39B / UAP56 Antibody - LS-C68164 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-DDX39B / UAP56 Antibody (clone 2060C10a) - LS-C184323 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2060C10a

Anti-DDX39B / UAP56 Antibody (Biotin) - LS-C211793 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Spliceosome RNA helicase DDX39B antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 47 kDa. Observed band size: 40 kDa Additional bands at: 60 kDa. We are unsure as to the identity of this extra band.

Anti-DDX39B / UAP56 Antibody (FITC) - LS-C211795 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Spliceosome RNA helicase DDX39B antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 47 kDa. Observed band size: 40 kDa Additional bands at: 60 kDa. We are unsure as to the identity of this extra band.

Anti-DDX39B / UAP56 Antibody - LS-C211794 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Spliceosome RNA helicase DDX39B antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 47 kDa. Observed band size: 40 kDa Additional bands at: 60 kDa. We are unsure as to the identity of this extra band.

Anti-DDX39B / UAP56 Antibody (N-Terminus) - LS-C110147 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DDX39B / UAP56 antibody LS-C110147 Western blot of OVCAR-3 cell lysate.

Anti-DDX39B / UAP56 Antibody (HRP) - LS-C211796 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Spliceosome RNA helicase DDX39B antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 47 kDa. Observed band size: 40 kDa Additional bands at: 60 kDa. We are unsure as to the identity of this extra band.

UAP56 Antibody - NBP1-31356 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UAP56 Antibody (2C5) - NBP2-02553 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C5
Western Blot: UAP56 Antibody (2C5) [NBP2-02553] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UAP56 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UAP56.

UAP56 Antibody - H00007919-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: UAP56 Antibody [H00007919-A01] - BAT1 polyclonal antibody (A01), Lot # GTH0060529QCS1 Western Blot analysis of BAT1 expression in Hela NE ( Cat # L013V3 ).

UAP56 Antibody - NBP1-32173 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-UAP56 Polyclonal Antibody - bs-3761R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human laryngeal tissue labeled with Rabbit Anti-UAP56 Polyclonal Antibody, Unconjugated(bs-3761R) 1:200 followed by conjugation to the secondary antibody and DAB staining
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