DDX39B

Gene Symbol DDX39B
Entrez Gene 7919
Alt Symbol BAT1, D6S81E, UAP56
Species Human
Gene Type protein-coding
Description DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
Other Description 56 kDa U2AF65-associated protein|ATP-dependent RNA helicase p47|HLA-B-associated transcript 1 protein|nuclear RNA helicase (DEAD family)|spliceosome RNA helicase BAT1|spliceosome RNA helicase DDX39B
Swissprots Q5STU4 Q5STB8 Q5STU5 O43496 Q2L6F9 Q13838 Q5RJ66 Q5STB4 B0S8C0 Q5ST94 Q71V76 Q0EFA1 Q5STB7 Q5RJ64 Q53GL9 Q5STB5 Q5STU8 Q5STU6
Accessions AAB94615 AAC63046 BAB63306 BAC54953 BAE78637 BAF31287 CAA75074 EAX03404 EAX03406 EAX03407 EAX03408 EAX03409 EAX03410 EAX03411 EAX03413 Q13838 AB209217 BAD92454 AK127767 AK222912 BAD96632 AK294939 BAG58016 AK295634 BAG58508 AK295854 BAG58660 AK298194 BAG60464 AK316469 BAH14840 BC000361 AAH00361 BC013006 AAH13006 BM993499 BT009909 AAP88911 BU628632 DA048099 DA272922 DQ891881 ABM82807 DQ895067 ABM85993 Z37166 CAA85523 NM_004640 NP_004631 NM_080598 NP_542165 NR_037852
Function Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. May undergo several rounds of ATP hydrolysis during assembly of TREX to drive subsequent loading of components such as ALYREF/THOC and CHTOP onto mRNA. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Also associates with pre-mRNA independent of ALYREF/THOC4 and the THO complex. Involved in the nuclear export of intronless mRNA; the ATP
Subcellular Location Nucleus. Nucleus speckle. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1. TREX complex assembly seems to occur in regions surrounding nuclear speckles known as perispeckles.
Top Pathways Spliceosome, RNA transport, mRNA surveillance pathway, Influenza A

BAT1 CRISPR/Cas9 KO Plasmid (h) - sc-403785 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 HDR Plasmid (h) - sc-403785-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 Double Nickase Plasmid (h) - sc-403785-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 Double Nickase Plasmid (h2) - sc-403785-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 CRISPR Activation Plasmid (h) - sc-403785-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 CRISPR Activation Plasmid (h2) - sc-403785-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 Lentiviral Activation Particles (h) - sc-403785-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 Lentiviral Activation Particles (h2) - sc-403785-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 siRNA (h) - sc-106930 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAT1 shRNA Plasmid (h) - sc-106930-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAT1 shRNA (h) Lentiviral Particles - sc-106930-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UAP56 RNAi - H00007919-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

UAP56 RNAi - H00007919-R04 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU116951 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3868 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3868 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01286 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01286

DDX39B siRNA (Human) - CRH5316 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DDX39B - MBS8229337 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DDX39 (NM_004640.6) - SHH275969 from Creative biogene

Category siRNA
Species Reactivities Human

BAT1 CRISPR/Cas9 KO Plasmid (h2) - sc-403785-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAT1 HDR Plasmid (h2) - sc-403785-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human DDX39B siRNA - orb265818 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DDX39B shRNA Plasmid (Human) - CHH5316 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DDX39B miRNA 3'UTR clone - MiUTR3H-01052 from Creative biogene

Species Reactivities Human
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