ZEB1

Gene Symbol ZEB1
Entrez Gene 6935
Alt Symbol AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A
Species Human
Gene Type protein-coding
Description zinc finger E-box binding homeobox 1
Other Description delta-crystallin enhancer binding factor 1|negative regulator of IL2|posterior polymorphous corneal dystrophy 3|transcription factor 8 (represses interleukin 2 expression)|zinc finger E-box-binding homeobox 1|zinc finger homeodomain enhancer-binding protein
Swissprots F5H4I8 E9PCM7 P37275 Q5T968 Q13800 Q8NB68 B4DJV0 Q12924 Q2KJ05 Q5VZ84 B4DUW9
Accessions CCO13853 CCQ43736 EAW85989 EAW85990 P37275 AI086650 AK091478 BAC03673 AK294775 BAG57903 AK296244 BAG58962 AK299541 BAG61488 AK299666 BAG61580 AK300830 BAG62481 AK307510 AK308785 AK308822 AK309331 AK309399 AK310924 AK311116 AK311137 AK311187 AK311201 AK311372 AK311557 AK314683 BAG37235 AL831979 BC009572 AAH09572 BC065705 BC107781 AAI07782 BC112392 AAI12393 BQ003893 BX111519 BX647794 DB442432 DC299346 M81699 U12170 AAA20602 XM_005252576 XP_005252633 XM_006717497 XP_006717560 XM_006717498 XP_006717561 XM_011519641 XP_011517943 XM_011519642 XP_011517944 XM_011519643 XP_011517945 XM_011519644 XP_011517946 XM_011519645 XP_011517947 XM_011519646 XP_011517948 XM_011519647 XP_011517949 XM_011519648 XP_011517950 NM_001128128 NP_001121600 NM_001174093 NP_001167564 NM_001174094 NP_001167565 NM_001174095 NP_001167566 NM_001174096 NP_001167567 NM_030751 NP_110378 NR_024285 NR_024286 NR_024287
Function Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. {ECO:0000269|PubMed:19935649, ECO:0000269|PubMed:20175752, ECO:0000269|PubMed:20418909}.
Subcellular Location Nucleus {ECO:0000269|PubMed:20418909}.
Tissue Specificity Colocalizes with SMARCA4/BRG1 in E-cadherin- negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level). Expressed in heart and skeletal muscle, but not in liver, spleen, or pancreas. {ECO:0000269|PubMed:20418909}.
Top Pathways MicroRNAs in cancer, Transcriptional misregulation in cancer

Zinc finger E-box-binding homeobox 1 (ZEB1), Human, ELISA Kit - CSB-EL026424HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Zinc finger E-box-binding homeobox 1 (ZEB1), Human, ELISA Kit - E01Z0024 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Zinc finger E-box-binding homeobox 1, ZEB1, Human, ELISA Kit - E14970h from ARP American Research Products

Category ELISA Kit
Prices $736.00
Sizes 96 t
Range 0.312-20 ng/mL

Zinc finger E box binding homeobox 1 (ZEB1), ELISA Kit - MBS7208048 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

zinc finger E-box binding homeobox 1, ELISA Kit - MBS910271 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human ZEB1 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 25 pg/ml -1600 pg/ml.

Zinc finger E-box-binding homeobox 1, ELISA Kit - MBS280255 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7203375 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7232860 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7240049 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7235965 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7222918 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7221901 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7235469 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7235759 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7247088 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Zinc finger E-box-binding homeobox 1 (ZEB1), ELISA Kit - MBS7223543 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Zinc finger E-box-binding homeobox 1(ZEB1) ELISA kit - CSB-EL026424HU from Cusabio

Category ELISA Kit
Sensitivity 6.25 pg/ml
Range 25 pg/ml-1600 pg/ml

Mouse ZEB1 / AREB6 ELISA Kit (Custom ELISA) - LS-F17562 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.312-20 ng/ml

Chicken ZEB1 / AREB6 ELISA Kit (Custom ELISA) - LS-F17560 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 0.312-20 ng/ml

Rat ZEB1 / AREB6 ELISA Kit (Custom ELISA) - LS-F17561 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.312-20 ng/ml

Human Zinc finger E-box-binding homeobox 1 ELISA Kit - abx250985 from Abbexa

Category ELISA Kit
Range 0.312 ng/ml - 20 ng/ml

Human ZEB1 / AREB6 ELISA Kit (Competitive EIA) - LS-F13505 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.312
Range 0.312-20 ng/ml

Human Zinc finger E-box-binding homeobox 1 (ZEB1) ELISA Kit - EKC36072 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 6.25 pg/ml
Range 25 pg/ml-1600 pg/ml

Human Zinc finger E-box-binding homeobox 1 ELISA Kit - EKE55128 from Biomatik

Category ELISA Kit
Prices $809.60, $3,440.80, $6,476.80
Sizes 96 t, 5x96t, 10x96t
Sensitivity The minimum detectable dose of this kit is typically less than 0.23 ng/ml
Range 0.312-20 ng/mL

ZEB1 - EKH3374 from Nordic BioSite

Sensitivity 0.188ng/ml
Range 0.312-20ng/ml
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