POSTN

Gene Symbol	POSTN
Entrez Gene	10631
Alt Symbol	OSF-2, OSF2, PDLPOSTN, PN, periostin
Species	Human
Gene Type	protein-coding
Description	periostin, osteoblast specific factor
Other Description	osteoblast specific factor 2 (fasciclin I-like)|periodontal ligament-specific periostin|periostin
Swissprots	Q5VSY5 Q15064 C0IMJ4 C0IMJ1 B1ALD8 Q8IZF9 Q15063 F5H628 D2KRH7 Q3KPJ5 Q29XZ0 C0IMJ2
Accessions	EAX08590 EAX08591 EAX08592 EAX08593 EAX08594 Q15063 AI580215 AK021444 AK297914 BAH12690 AK300261 BAH13247 AK304640 BAG65419 AY140646 AAN17733 AY918092 AAY15840 BC106709 AAI06710 BC106710 AAI06711 BG938993 BP335818 BQ575951 BY795054 D13665 BAA02836 D13666 BAA02837 DC403736 EU262883 ABY86630 EU262884 ABY86631 EU262885 ABY86632 EU262886 ABY86633 GU354210 ADA79517 XM_005266231 XP_005266288 XM_005266232 XP_005266289 NM_001135934 NP_001129406 NM_001135935 NP_001129407 NM_001135936 NP_001129408 NM_001286665 NP_001273594 NM_001286666 NP_001273595 NM_001286667 NP_001273596 NM_006475 NP_006466
Function	Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity). Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. {ECO:0000250, ECO:0000269|PubMed:12235007, ECO:0000269|PubMed:18450759}.
Subcellular Location	Golgi apparatus {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12235007}. Note=Colocalizes with BMP1 in the Golgi. {ECO:0000250}.
Tissue Specificity	Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers. {ECO:0000269|PubMed:11550156, ECO:0000269|PubMed:12235007, ECO:0000269|PubMed:15082792, ECO:0000269|PubMed:23946676}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Periostin full length protein - ab188464 from Abcam Category Protein Source HEK 293 cells Species Human

Human Periostin protein fragment - ab203522 from Abcam Category Protein Source E. coli Species Human

Human Periostin protein fragment - ab73235 from Abcam Category Protein Source E. coli Species Human

Periostin peptide - ab90847 from Abcam Category Peptide

POSTN / Periostin Antibody Blocking Peptide - LS-E1331 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POSTN / Periostin Antibody Blocking Peptide - LS-E15299 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POSTN / Periostin Blocking Peptide - LS-E15300 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POSTN-Antibody-C-term-Blocking-peptide - BP11962b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Periostin/OSF-2, CF - 3548-F2-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Asn22-Gln836, with a C-terminal 6-His tag

Periostin Protein (OPPA00711) - OPPA00711 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human POSTN protein - orb244813 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human Periostin protein - orb80549 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Human POSTN His tag protein - orb83227 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 50 μg, 100 μg Source Human Species Human

POSTN Blocking Peptide - 33R-9848 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

POSTN Blocking Peptide - 33R-7797 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Periostin Protein - abx068464 from Abbexa Category Protein Source E.coli Species Human

Periostin Peptide - AC21-2904-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Periostin (His-tagged Fusion Protein) - PA514X from Acris Antibodies Category Protein Prices $550.00 Sizes 100 µg Source E. coli Species Human

Periostin, Human Recombinant - 228-11225-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human Periostin - 228-11225-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Periostin - 228-11225-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

Periostin (POSTN), Human - 20-9251 from ARP American Research Products Category Protein Prices $429.00 Sizes 50 µg Source E.coli Species Human

POSTN fusion protein - ag13791 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

POSTN fusion protein - Ag14487 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Periostin Human - CYPS-459 from NeoScientific Category Protein Prices $65.00, $169.00, $4,680.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

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